195535-07-0Relevant academic research and scientific papers
Gold-catalyzed highly regioselective oxidation of C-C triple bonds without acid additives: Propargyl moieties as masked α,β-unsaturated carbonyls
Lu, Biao,Li, Chaoqun,Zhang, Liming
supporting information; experimental part, p. 14070 - 14072 (2011/01/04)
Gold-catalyzed intermolecular oxidations of internal alkynes have been achieved with high regioselectivities using 8-alkylquinoline N-oxides as oxidants and in the absence of acid additives. Synthetically versatile α,β-unsaturated carbonyls are obtained in good to excellent yields and with excellent E-selectivities. A range of functional groups such as THP, MOMO, N3, OTBS, and N-Boc are tolerated. This reaction allows α,β-unsaturated carbonyls to be masked as propargyl moieties, thus offering a practical solution to compatibility issues with these functional groups likely encountered in syntheses of complex structures.
Sequential cyclization/silylation of enynes catalyzed by an organoyttrium complex
Molander, Gary A.,Retsch, William H.
, p. 8817 - 8825 (2007/10/03)
The organoyttrium complex Cp*2YCH3·THF (Cp* = C5Me5) has been shown to be an effective precatalyst for the selective sequential cyclization/silylation of 1,6- and 1,7-enynes. The catalyst's ability to insert the
