195724-23-3

Basic information

• Product Name: [1,2]Dithiolan-3-yl-acetic acid 4-nitro-phenyl ester
• CAS NO: 195724-23-3
• Molecular Weight: 285.345
• Mol File: 195724-23-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1,2]Dithiolan-3-yl-acetic acid 4-nitro-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [1,2]Dithiolan-3-yl-acetic acid 4-nitro-phenyl ester(195724-23-3)
• EPA Substance Registry System: [1,2]Dithiolan-3-yl-acetic acid 4-nitro-phenyl ester(195724-23-3)

Safety Data

• Hazardous Substances Data: 195724-23-3(Hazardous Substances Data)

Upstream product

• 195724-20-0 Thioacetic acid S-[3-acetylsulfanyl-1-(2,2-dimethyl-4,6-dioxo-[1,3]dioxan-5-yl)-propyl] ester 
• 195724-21-1 2-(1,3-Bis-acetylsulfanyl-propyl)-malonic acid monomethyl ester 
• 195724-22-2 2-[1,2]Dithiolan-3-yl-malonic acid dimethyl ester 
• 36305-11-0 2-(1,2-dithiolan-3-yl)acetic acid 
• 658-78-6 1-nitro-4-trifluoroacetoxy-benzene 

Relevant articles and documents

An efficient synthetic route to 2-(1,2-dithiolan-3-yl)acetic acid. Trisnorlipoic acid and amide derivatives

A simple, efficient synthesis of 2-(1,2-dithiolan-3-yl)acetic acid from Meldrum's acid, acrolein and thioacetic acid is described. The isopropyldene 2,4-bis(acetylthio)butane-1,1-dicarboxyl formed in the three-component, single container process, can be methanolized to the corresponding dimethyl ester and then hydrolyzed, oxidized to the disulfide and decarboxylated to 2-(1,2-dithiolan-3-yl)acetic acid. The acid can be converted by conventional reagents into a variety of amide derivatives.