19579-43-2

Upstream product

• 106-49-0 p-toluidine 
• 127099-85-8 N-Cyanoguanidine 

Downstream Products

• 113795-58-7 6-methyl-6-(2-morpholin-4-yl-ethyl)-1-p-tolyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine 
• 511514-31-1 6-[(1H-benzo[d]imidazol-2-ylthio)methyl]-N₂-p-tolyl-1,3,5-triazine-2,4-diamine 
• 1269527-18-5 6-[(5-methyl-1H-benzo[d]imidazol-2-ylthio)methyl]-N₂-p-tolyl-1,3,5-triazine-2,4-diamine 
• 99860-36-3 6-chloromethyl-N-p-tolyl-[1,3,5]triazine-2,4-diamine 
• 139424-37-6 4,6-Diamino-1,2-dihydro-1-(4-methylphenyl)-2-styryl-1,3,5-triazinhydrochlorid 
• 139424-36-5 4,6-Diamino-1,2-dihydro-1-(4-methylphenyl)-2-styryl-1,3,5-triazin 
• 93002-59-6 methyl 4-amino-6-(p-tolylamino)-1,3,5-triazine-2-carboxylate 
• 101271-12-9 6-methyl-6-morpholin-4-ylmethyl-1-p-tolyl-1,6-dihydro-[1,3,5]triazine-2,4-diamine 

Relevant academic research and scientific papers

Synthesis and antiviral activity of benzimidazolyl-and triazolyl-1,3,5- triazines

A novel series of 1,3,5-triazine analogs was successfully synthesized through conjugation with benzimidazole or 1,2,4-triazole derivatives via a methylenethio linker. The new analogs were in vitro evaluated against HSV-1 in Vero cells; among these analogs, two compounds exhibited good effect in inhibiting HSV-1 replication (for compound 5p: EC50 = 3.5 μg/ml, SI = 358; for compound 5r: EC50 = 5.0 μg/ml, SI = 300) in comparison to acyclovir. Springer Science+Business Media, LLC 2011.

Incorporation of a Biguanide Scaffold Enhances Drug Uptake by Organic Cation Transporters 1 and 2

Membrane transporters play a significant role in the transport of many endogenous and exogenous compounds. The knowledge of transporter substrate requirements has allowed further development of drugs that utilize them to ensure tissue permeation. In this