19614-11-0Relevant academic research and scientific papers
ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS
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Page/Page column 102, (2017/08/01)
A compound of formula (I) for use in the prevention or treatment of a bacterial infection.
Catalytic chemical amide synthesis at room temperature: One more step toward peptide synthesis
Mohy El Dine, Tharwat,Erb, William,Berhault, Yohann,Rouden, Jacques,Blanchet, Jér?me
, p. 4532 - 4544 (2015/05/13)
An efficient method has been developed for direct amide bond synthesis between carboxylic acids and amines via (2-(thiophen-2-ylmethyl)phenyl)boronic acid as a highly active bench-stable catalyst. This catalyst was found to be very effective at room temperature for a large range of substrates with slightly higher temperatures required for challenging ones. This methodology can be applied to aliphatic, α-hydroxyl, aromatic, and heteroaromatic acids as well as primary, secondary, heterocyclic, and even functionalized amines. Notably, N-Boc-protected amino acids were successfully coupled in good yields with very little racemization. An example of catalytic dipeptide synthesis is reported.
Synthesis and structure of organobismuth chlorides and triflates containing (C,E)-chelating ligands (E=O, S) and their catalytic application in the allylation of aldehydes with tetraallyltin
Tan, Nianyuan,Chen, Yi,Zhou, Yongbo,Au, Chak-Tong,Yin, Shuang-Feng
, p. 1363 - 1369 (2013/12/04)
Four air-stable hypervalent organobismuth compounds with (C,O)- or (C,S)-chelating ligands, namely, R2BiCl (R=2-(MeECH 2)C6H4; E=O (3), S (4)), [2-(MeOCH 2)C6H4]2BiOTf
Efficient and highly selective method for the synthesis of 4-Iodo-3-substituted 1 H -Isoselenochromenes and -isothiochromenes
Schneider, Caroline C.,Bortolatto, Cristiani,Back, Davi F.,Menezes, Paulo H.,Zeni, Gilson
supporting information; experimental part, p. 413 - 418 (2011/03/22)
We present here our results on the preparation of 2-alkynylbenzyl selenide and sulfide derivatives via Sonogashira cross-coupling of benzyl chalcogenides with different alkynes. This cross-coupling reaction proceeded cleanly under mild conditions and was performed with propargyl alcohol as well as alkyl- and arylalkynes. Subsequent electrophilic-cyclization reaction of the 2-alkynylbenzyl selenide and sulfide derivatives using iodine as an electrophilic source gave 4-iodo-3-substituted 1H-isoselenochromenes and -isothiochromenes in moderate yields. The unique product obtained during the course of this cyclization contained a six-membered ring which was confirmed by X-ray diffraction analysis. Georg Thieme Verlag Stuttgart - New York.
Superelectrophilic methylthiomethylation of aromatics with chloromethyl methyl sulfide/aluminum chloride (MeSCH2Cl:2 AlCl3) reagent
Olah,Wang,Neyer
, p. 276 - 278 (2007/10/02)
Effective methylthiomethylation of aromatics was achieved by using chloromethyl methyl sulfide/aluminum chloride (MeSCH2Cl:2 AlCl3) as the alkylating agent. Excess aluminum chloride activates the thiocarboxonium ion intermediate by coordinating with sulfur and thus diminishes back donation of 'electron density' into the carbocationic center, rendering it a superelectrophilic methylthiomethylating agent.
Initiators for polymerization
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, (2008/06/13)
Initiators for cationic polymerization by thermal activation, photochemical activation (UV-irradiation) or activation by electron bombardment are compounds wherein a heterocyclic, aryl substituted or aryl ring is fused to a sulfonium moiety in combination
NOVEL AND EFFECTIVE METHODS FOR α-THIOALKYLATION OF AROMATIC COMPOUNDS
Torisawa, Yasuhiro,Satoh, Atsushi,Ikegami, Shiro
, p. 1729 - 1732 (2007/10/02)
Convenient and effective methods for the introduction of a methylthiomethyl group and other α-thioalkyl group into aromatic compounds are described.
