19634-93-6

Usage

Uses

Used in Pharmaceutical Manufacturing:
2,3,4,4a,10,10a-hexahydrophenanthren-9(1H)-one is used as a precursor in the synthesis of various medications. Its unique chemical structure and properties make it a valuable component in the development of new pharmaceutical compounds.
Used in Research and Development:
2,3,4,4a,10,10a-hexahydrophenanthren-9(1H)-one may also have potential applications in the research and development of new chemical compounds and materials. Its versatile chemical properties and solubility in organic solvents make it a promising candidate for further exploration and innovation in the scientific community.

Upstream product

• 16306-39-1 cis-1,2,3,4,4a,9,10,10a-octahydrophenanthrene 
• 16306-39-1 1,2,3,4,4a,9,10,10a-octahydrophenanthrene 
• 186581-53-3 diazomethane 
• 1203-67-4 cis-1,2,3,4,4a,9a-hexahydro-9H-fluoren-9-one 
• 124620-30-0 1-phenethyl-cyclohexanol 
• 17040-65-2 1-cyclohexenyl(phenyl)methanone 
• 16306-39-1 (-)-cis-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene 
• 82031-71-8 (1R*,2S*)-2-(phenylethynyl)cyclohexanol 
• 36449-64-6 (-)-trans-2-phenethyl-cyclohexanol 
• 24731-17-7 ethyl 2-(2-oxocyclohexyl)acetate 
• 21405-66-3 7A-phenyl-hexahydro-benzofuran-2-one 
• 532-27-4 1-chloroacetophenone 
• 110-83-8 cyclohexene 
• 52092-27-0 (+/-)-(cis-2-phenyl-cyclohexyl)-acetic acid 

Downstream Products

• 16804-85-6 (+/-)-cis-1.2.3.4.4a.10a-Hexahydro-phenanthren 
• 7498-82-0 (+/-)-9-semicarbazono-cis-1.2.3.4.4a.9.10.10a-octahydro-phenanthrene 

Relevant academic research and scientific papers

Oxidative Kinetic Resolution of cis -Fused Tricyclic 1-Tetralone Derivatives by Guanidine-Bisurea Bifunctional Organocatalyst

We present an enantioselective synthesis of cis -fused tricyclic 1-tetralones via oxidative kinetic resolution in the presence of cumene hydroperoxide (CHP) and guanidine-bisurea bifunctional organocatalyst. This reaction affords the corresponding α-hydroxylation products together with unreacted tetralones in good to high enantioselectivity, with s values as high as 42. The reaction was successfully applied for the synthesis of the core structure of a kainoid derivative, 4-(2-methoxyphenyl)-2-carboxy-3-pyrrolidineacetic acid (MFPA).

Metal-catalyzed organic photoreactions. Photoreaction of 2-chloroacetophenone derivatives with olefins in the presence of silver trifluoromethanesulfonate

UV-irradiation of 2-chloroacetophenones and olefins in the presence of silver triflate affords naphthalenone derivatives with high regio and stereoselectivity and chemical yields. A possible mechanism is proposed.

METAL-CATALYZED ORGANIC PHOTOREACTIONS. PHOTOREACTION OF OLEFINS WITH 2-CHLOROACETOPHENONE IN THE PRESENCE OF SILVER TRIFLUOROMETHANESULFONATE

Under UV irradiation with 2-chloroacetophenone in the presence of silver trifluoromethanesulfonate in acetonitrile, acyclic olefins gave naphtalenone derivatives, while cyclic olefins gave phenantrone derivatives in moderate yields.