196500-09-1

Basic information

• Product Name: 2-METHYL-3-NITROBENZYL METHANESULFONATE
• Synonyms: 2-METHYL-3-NITROBENZYL METHANESULFONATE
• CAS NO: 196500-09-1
• Molecular Formula: C₉H₁₁NO₅S
• Molecular Weight: 245.25
• Mol File: 196500-09-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-METHYL-3-NITROBENZYL METHANESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-3-NITROBENZYL METHANESULFONATE(196500-09-1)
• EPA Substance Registry System: 2-METHYL-3-NITROBENZYL METHANESULFONATE(196500-09-1)

Safety Data

• Hazardous Substances Data: 196500-09-1(Hazardous Substances Data)

Usage

Uses

2-Methyl-3-nitrobenzyl Mesylate is used in preparation of Ropinirole Hydrochloride.

Upstream product

• 23876-13-3 (2-methyl-3-nitrophenyl)methanol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 23876-14-4 3-nitro-2-methylphenylacetonitrile 
• 215930-27-1 2-Amino-N-methyl-N-[2-methyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenyl]-acetamide 
• 179626-03-0 2-Methyl-3-(2-methyl-quinolin-8-yloxymethyl)-phenylamine 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF INDOLONE DERIVATIVE

A process for the preparation of 4-[2-(Di-n-propylamino) ethyl]-2,3-dihydro-1 H-indol-2-one of formula (I) and its pharmaceutically acceptable salts, solvates Formaula I involving new intermediates of compound of formula (A) and (B) wherein R represents (i) a halogen atom selected from fluorine, chlorine atom, bromine atom and iodine atom; (ii) lower alkanesulfonyloxy group selected from methanesulfonyloxy, ethanesulfonyloxy, isopropanesulfonyloxy, propanesulfonyloxy, butanesulfonyloxy, tert-butanesulfonyloxy, pentanesulfonyloxy, hexanesulfonyloxy; (iii) substituted or unsubstantiated arylsulfonyloxy group selected from phenylsulfonyloxy, 4-methylphenylsulfonyloxy, 2-methylphenylsulfonyloxy, 4- nitrophenylsulfonyloxy, 4- methoxyphenylsulfonyloxy, 3-chlorophenylsulfonyloxy; (iv) arylalkylsulfonyloxy group selected from benzylsulfonyloxy, 2- phenylethylsulfonyloxy, 4-phenylbutylsulfonyloxy, 4- methylbenzylsulfonyloxy, 2- methylbenzylsulfonyloxy, 4- nitrobenzylsulfonyloxy, 4-methoxybenzylsulfonyloxy, 3- chlorobenzylsulfonyloxy.

A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 4. Discovery of novel frameworks mimicking the active conformation

In recent articles we reported the identification of a series of 8- [[2,6-dichloro-3-[N-methyl-N-[(E)- (substituted)acryloylglycyl]amino]benzyl]oxy]-2-methylimidazo[1,2- a]pyridines as the first orally active non-peptide bradykinin (BK) B2 rece