19673-90-6 Usage
Uses
Used in Organic Synthesis:
6-Bromo-4-methoxy-5-methylthieno[2,3-d]pyrimidine is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows for the formation of new chemical bonds and the creation of diverse molecular architectures.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 6-Bromo-4-methoxy-5-methylthieno[2,3-d]pyrimidine is used as a research compound to explore its potential as a therapeutic agent. Its heterocyclic nature and functional groups may contribute to its interaction with biological targets, offering possibilities for the development of new drugs.
Used as a Building Block for Complex Molecules:
6-Bromo-4-methoxy-5-methylthieno[2,3-d]pyrimidine is utilized as a building block in the synthesis of more complex molecules, such as pharmaceuticals, agrochemicals, and other specialty chemicals. Its structural features can be incorporated into larger molecules to enhance their properties and functions.
Used in Drug Development:
Due to its unique chemical structure, 6-Bromo-4-methoxy-5-methylthieno[2,3-d]pyrimidine may have potential applications in the development of new drugs. Its ability to interact with biological targets could lead to the discovery of novel therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Development:
Similarly, 6-BroMo-4-Methoxy-5-Methylthieno[2,3-d]pyriMidine may also find applications in the development of new agrochemicals, such as pesticides and herbicides. Its potential to modulate biological processes could contribute to the creation of more effective and targeted agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 19673-90-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,6,7 and 3 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 19673-90:
(7*1)+(6*9)+(5*6)+(4*7)+(3*3)+(2*9)+(1*0)=146
146 % 10 = 6
So 19673-90-6 is a valid CAS Registry Number.
19673-90-6Relevant academic research and scientific papers
Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase
Park, Jaeok,Leung, Chun Yuen,Matralis, Alexios N.,Lacbay, Cyrus M.,Tsakos, Michail,Fernandez De Troconiz, Guillermo,Berghuis, Albert M.,Tsantrizos, Youla S.
, p. 2119 - 2134 (2017/03/17)
The human farnesyl pyrophosphate synthase (hFPPS), a key regulatory enzyme in the mevalonate pathway, catalyzes the biosynthesis of the C-15 isoprenoid farnesyl pyrophosphate (FPP). FPP plays a crucial role in the post-translational prenylation of small GTPases that perform a plethora of cellular functions. Although hFPPS is a well-established therapeutic target for lytic bone diseases, the currently available bisphosphonate drugs exhibit poor cellular uptake and distribution into nonskeletal tissues. Recent drug discovery efforts have focused primarily on allosteric inhibition of hFPPS and the discovery of non-bisphosphonate drugs for potentially treating nonskeletal diseases. Hit-to-lead optimization of a new series of thienopyrimidine-based monosphosphonates (ThP-MPs) led to the identification of analogs with nanomolar potency in inhibiting hFPPS. Their interactions with the allosteric pocket of the enzyme were characterized by crystallography, and the results provide further insight into the pharmacophore requirements for allosteric inhibition.
