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43088-67-1

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43088-67-1 Usage

General Description

4-Chloro-5-methylthieno[2,3-d]pyrimidine is a chemical compound with the molecular formula C6H5ClN2S. It is a heterocyclic compound that contains a thieno pyrimidine ring system. 4-Chloro-5-methylthieno[2,3-d]pyrimidine is commonly used in the field of pharmaceuticals and agrochemicals as a building block in the synthesis of various biologically active compounds. It is also employed in the research and development of new drugs due to its potential pharmacological activities. 4-Chloro-5-methylthieno[2,3-d]pyrimidine may also be used in the production of other specialty chemicals and materials, making it a versatile and important component in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 43088-67-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,3,0,8 and 8 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 43088-67:
(7*4)+(6*3)+(5*0)+(4*8)+(3*8)+(2*6)+(1*7)=121
121 % 10 = 1
So 43088-67-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H5ClN2S/c1-4-2-11-7-5(4)6(8)9-3-10-7/h2-3H,1H3

43088-67-1Relevant articles and documents

Stimulation of cortical bone formation with thienopyrimidine based inhibitors of Notum Pectinacetylesterase

Tarver, James E.,Pabba, Praveen K.,Barbosa, Joseph,Han, Qiang,Gardyan, Michael W.,Brommage, Robert,Thompson, Andrea Y.,Schmidt, James M.,Wilson, Alan G.E.,He, Wei,Lombardo, Victoria K.,Carson, Kenneth G.

, p. 1525 - 1528 (2016/07/27)

A group of small molecule thienopyrimidine inhibitors of Notum Pectinacetylesterase are described. We explored both 2-((5,6-thieno[2,3-d]pyrimidin-4-yl)thio)acetic acids and 2-((6,7-thieno[3,2-d]pyrimidin-4-yl)thio)acetic acids. In both series, highly potent, orally active Notum Pectinacetylesterase inhibitors were identified.

NOVEL THIENOPYRIMIDINE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

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, (2010/11/28)

The present invention relates to a novel thienopyrimidine derivative having an excellent anti? inflammatory and anti-cancer activity, or a pharmaceutically acceptable salt thereof, a process for the preparation thereof and a pharmaceutical composition comprising the same. The compound according to the present invention strongly inhibits IKB kinase-β (IKK-β) involved in the activation of a transcriptional factor, NF-κB, which is associated with inducing various immune and inflammatory diseases, whereby a composition comprising the compound is a useful therapeutic agent against inflammatory diseases, in particular, arthritis and cancer.

SUBSTITUTED AMINOPYRIMIDINES AS NEUROKININ ANTAGONISTS

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Page 49; 51, (2008/06/13)

The invention discloses tachykinin receptor antagonists. The tachykinin family of receptors comprising the neurokinins substance P (SP), neurokinin A, and neurokinin B and related neuropeptides that are widely distributed in the peripheral and central ner

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