196867-32-0

Basic information

• Product Name: 1-(3',5'-di-O-benzoyl-2'-deoxy-2'-iodo-β-D-xylopentofuranosyl)thymine
• Synonyms: 1-(3',5'-di-O-benzoyl-2'-deoxy-2'-iodo-β-D-xylopentofuranosyl)thymine
• CAS NO: 196867-32-0
• Molecular Weight: 576.344
• Mol File: 196867-32-0.mol

Chemical Properties

• CAS DataBase Reference: 1-(3',5'-di-O-benzoyl-2'-deoxy-2'-iodo-β-D-xylopentofuranosyl)thymine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3',5'-di-O-benzoyl-2'-deoxy-2'-iodo-β-D-xylopentofuranosyl)thymine(196867-32-0)
• EPA Substance Registry System: 1-(3',5'-di-O-benzoyl-2'-deoxy-2'-iodo-β-D-xylopentofuranosyl)thymine(196867-32-0)

Safety Data

• Hazardous Substances Data: 196867-32-0(Hazardous Substances Data)

Upstream product

• 65-71-4 thymin 
• 191538-87-1 C₁₉H₁₆O₅ 
• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 

Downstream Products

• 14486-22-7 1-(2,3-anhydro-β-D-lyxofuranosyl)thymine 
• 70838-47-0 (2R,3R,5R)-2-(benzoyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-tetrahydrofuran-3-yl benzoate 
• 122567-97-9 5′-benzoyl-2′,3′-didehydro-3′-deoxythymidine 
• 16053-52-4 threothymidine 

Relevant articles and documents

An efficient and highly stereoselective synthesis of nucleoside derivatives from furanoid 1,2-diols

Reaction between suitably protected furanoid glycals 1b-4b, readily obtained from furanoid 1,2-diols (1a-4a), and different silylated pyrimidine bases, gave the corresponding 3',5'- and 3',5',6'-O-protected 2'-deoxy-2'-iodo-β-D-xylo-pentofuranosyl 5-10 and β-D-gluco-hexofuranosyl 11 nucleosides, respectively. Compound 5 has been transformed into its 2'-deoxy 12 and 2',3'-anhydro 14 derivatives. The high stereoselectivity of the reaction is discussed.