19688-95-0

Usage

Uses

Used in Pharmaceutical Research:
Thiocyanic acid, 5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl ester is used as a potential drug candidate in pharmaceutical research for its promising pharmacological properties. Its unique chemical structure and properties make it a viable candidate for further research and development in the field of medicinal chemistry.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, Thiocyanic acid, 5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl ester is utilized for its potential use in the treatment of various medical conditions. Its chemical structure allows for the exploration of its therapeutic potential, making it a valuable compound for the development of new drugs and therapies.
Used in Drug Development:
Thiocyanic acid, 5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl ester is employed in drug development as a starting point for the synthesis of new pharmaceutical agents. Its unique properties and potential therapeutic effects make it a valuable component in the creation of novel drugs to address various medical conditions.
Used in Treatment of Medical Conditions:
Although specific medical conditions have not been mentioned in the provided materials, Thiocyanic acid, 5-amino-3-methyl-1-phenyl-1H-pyrazol-4-yl ester has been studied for its potential use in the treatment of various medical conditions. Its pharmacological properties and chemical structure make it a promising candidate for the development of treatments for a range of diseases and disorders.

Upstream product

• 100-63-0 phenylhydrazine 
• 1131-18-6 1-Phenyl-3-methyl-5-aminopyrazole 
• 540-72-7 sodium thiocyanide 
• 1147550-11-5 ammonium thiocyanate 
• 333-20-0 potassium thioacyanate 

Downstream Products

• 53865-72-8 3,5-dimethyl-1-phenylpyrazolo<3,4-d>thiazole 
• 96497-49-3 5-amino-3-methyl-1-phenylpyrazole-4-thiol 

Relevant academic research and scientific papers

Visible-light enabled C4-thiocyanation of pyrazoles by graphite-phase carbon nitride (g-C3N4)

Thiocyanation is an important and effective way to form C[sbnd]S bonds in organic synthetic methodology. Especially, thiocyanation of pyrazole attracts the attention of many researchers because sulfur-containing compounds are widely applied in many crucial fields such as organic materials, agrochemistry, nanotechnology, etc. Herein, we described A rapid metal- and additive-free method for C(sp2)-H thiocyanation of pyrazoles under visible light at room temperature by using a sustainable catalyst of graphite-phase carbon nitride (g-C3N4) and a thiocyanating agent of ammonium thiocyanate. The method presents many advantages, such as usage of eco-friendly photoredox catalyst, a wide range of substrates and a good yield of products, etc.

Hydrogen Peroxide-Mediated Rapid Room Temperature Metal-Free C(sp2)-H Thiocyanation of Amino Pyrazoles, Amino Uracils, and Enamines

A rapid metal-and additive-free room temperature method for C(sp2)-H thiocyanation of aminopyrazoles, aminoisoxazole, aminoisothiazole, amino uracils, and aliphatic enamines has been developed in an aqueous medium using hydrogen peroxide as a benign oxidant and ammonium thiocyanate as a thiocyanating agent. On the other hand, the reaction of hydrogen peroxide and ammonium thiocyanate followed by one-pot addition of NaOH provides the corresponding disulfides in the case of amino azoles, and pyrimidine-fused 2-amino thiazoles were observed in the case of aminouracils. The salient features of this method are the use of an eco-friendly oxidant, reaction tunability to access different products, wide substrate scope, and good to very good yields.

Synthesis of Pyrazolothiazoles

Several 5-substituted 1-phenylpyrazolothiazole derivatives have been synthesized by reaction of 5-amino-3-methyl-1-phenylpyrazole-4-thiol with different reagents.