196882-98-1

Basic information

• Product Name: 1-Benzenesulfonyl-5-methoxy-1,2,3,6-tetrahydro-pyridine
• Synonyms: 1-Benzenesulfonyl-5-methoxy-1,2,3,6-tetrahydro-pyridine
• CAS NO: 196882-98-1
• Molecular Weight: 253.322
• Mol File: 196882-98-1.mol

Chemical Properties

• CAS DataBase Reference: 1-Benzenesulfonyl-5-methoxy-1,2,3,6-tetrahydro-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzenesulfonyl-5-methoxy-1,2,3,6-tetrahydro-pyridine(196882-98-1)
• EPA Substance Registry System: 1-Benzenesulfonyl-5-methoxy-1,2,3,6-tetrahydro-pyridine(196882-98-1)

Safety Data

• Hazardous Substances Data: 196882-98-1(Hazardous Substances Data)

Upstream product

• 267666-10-4 N-benzenesulfonyl-3-piperidone 
• 98-09-9 benzenesulfonyl chloride 
• 1027657-45-9 1-benzenesulfonyl-3,3-dimethoxy-piperidine 

Downstream Products

• 196883-02-0 2,9-bis-benzenesulfonyl-7-methoxy-2,3,4,9-tetrahydro-1H-β-carbolin-6-ol 

Relevant articles and documents

Lewis Acid-Directed Cyclocondensation of Piperidone Enol Ethers with 2-Methoxy-4-(N-phenylsulfonyl)-1,4-benzoquinoneimine: A New Regioselective Synthesis of Oxygenated Carbolines

Lewis acid-directed cyclocondensations of piperidone enol ethers with 2-methoxy-4-(N-phenylsulfonyl)-1,4-henzoquinoneimine are reported. Benzofurans are obtained with BF3·OEt2 as a promoter, whereas use of excess amounts of TiCl4:Ti(OiPr)4 leads to tetrahydrocarbolines. The latter reactions provide expedient routes to oxygen-substituted tetrahydrocarbolines and carbolines. As applications of this new methodology, the preparations of 1-[3-(dimethylamino)propyl]amino-7-methoxy- and 1-[3-(dimethylamino)propyl]amino-7,8-dimethoxy-5H-pyrido[4,3-b]indoles are described.