19690-13-2

Usage

Uses

Used in Pharmaceutical Research and Development:
(2-PYRIDIN-3-YLETHYL)METHYLAMINE is used as a key intermediate in the synthesis of various pharmaceuticals due to its ability to form stable bonds with other molecules. Its presence in the molecular structure can enhance the pharmacological properties of the resulting compounds, making it a valuable component in drug discovery and development.
Used in Agrochemical Production:
In the agrochemical industry, (2-PYRIDIN-3-YLETHYL)METHYLAMINE is used as a precursor in the creation of various agrochemicals. Its incorporation can lead to the development of more effective and targeted pesticides or herbicides, contributing to improved agricultural practices and crop protection.
Used in Organic Synthesis:
(2-PYRIDIN-3-YLETHYL)METHYLAMINE is utilized as a versatile building block in organic synthesis for the creation of a wide range of organic compounds. Its reactivity and structural features make it suitable for use in the synthesis of complex organic molecules, including those with potential applications in various industries.
Used in the Development of New Drugs and Biologically Active Compounds:
(2-PYRIDIN-3-YLETHYL)METHYLAMINE is employed as a component in the research and development of new drugs and biologically active compounds. Its unique structure allows it to be a part of molecules with potential therapeutic effects, contributing to the advancement of medicine and healthcare.

InChI:InChI=1/C8H12N2/c1-9-6-4-8-3-2-5-10-7-8/h2-3,5,7,9H,4,6H2,1H3

Upstream product

• 106271-65-2 N-methyl-2-pyridin-3-yl-acetamide 
• 864960-87-2 benzyl-methyl-(2-pyridine-3-yl-ethyl-)amine 
• 501-81-5 pyridyl-3-yl-acetic acid 
• 6419-36-9 3-pyridineacetic acid hydrochloride 

Downstream Products

• 128225-20-7 trans-(+/-)-N,N'-Dimethyl-N-<2-(3-pyridyl)ethyl>-1,2-cyclohexanediamine 

Relevant academic research and scientific papers

Heterocyclic compound having oxime group

The present invention provides a compound that has an excellent inhibitory activity on STAT6 activation and is effective against allergic diseases, and a medicinal composition thereof. According to the present invention, disclosed is the compound represented by the General Formula (I) [where R1 and R2 independently represent a C1-6 alkyl group and the like that may have a hydrogen atom or a substituent; R3 represents a C1-6 alkyl group and the like that may have a substituent; R4 and R5 independent represents a hydrogen atom or a C1-6 alkyl group and the like that may have a substituent; R6 represents a hydrogen atom and the like; W represents —SO2— and the like; and X represents a sulphur atom and the like.]or a salt thereof, or a hydrate thereof.

Nucleophilic Addition of 2-, 3-, or 4-pyridine to the Aziridine, 7-Methyl-7-azabicycloheptane

The synthesis of trans-(+/-)-N-methyl-N-amino>cyclohexyl>-4-benzofuranacetamide dihydrochloride, 1 which is a 3-pyridyl derivative of the kappa opioid analgesic trans-(+/-)-N-methyl-N-benzofuran-4-acetamide monohydrochloride, 2 is described.The key intermediate is trans-(+/-)-N,N'-dimethyl-N--1,2-cyclohexanediamine, 9 which is formed by nucleophilic addition of 3-pyridine 6 to the aziridine, 7-methyl-7-azabicycloheptane, 4.During attempts to prepare the 2- or 4-isomeric pyridyl derivatives of 1 it was discovered that both 2- or 4-pyridine, 5 or 7 are converted to N-methyl-N,N-di- 11 and N-methyl-N,N-di 13 respectively by refluxing in toluene in the presence of ammonium chloride.The 3-isomer, 6 is unchanged after treatment under identical conditions.Careful control of the reaction conditions enabled the aziridine 4 to be ring opened with the pyridyl amines 5 or 7 to give the 1,2-diamines trans-(+/-)-N,N'-dimethyl-N--1,2-cyclohexanediamine, 8 or trans-(+/-)-N,N'-dimethyl-N--1,2-cyclohexane diamine 10 respectively.