6419-36-9Relevant articles and documents
Preparation method of 3-pyridylacetic acid hydrochloride
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Paragraph 0020; 0023; 0024; 0025; 0028; 0029, (2017/02/28)
The invention discloses a preparation method of 3-pyridylacetic acid hydrochloride and belongs to the field of chemistry. A 3-pyridylacetic acid hydrochloride product is prepared from 3-methylpyridine chlorination side product 2-chloro-3-methylpyridine as a raw material through cyanidation, alkaline hydrolysis, hydrogenation reduction and salification. The 3-pyridylacetic acid hydrochloride product has purity of 98.5% or more.
Novel Process For Preparing Risedronic Acid
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Page/Page column 4, (2010/06/11)
The present invention relates to a process for preparing risedronic acid comprising the step of combining a 3-pyridyl acetic acid or a salt thereof, phosphorous acid, and a halophosporous compound selected from PCl3, PClS, POCl3, PBr3, POBr3, and PBr5 in the presence of a diluent that is either a bicyclic aliphatic hydrocarbon or a substituted cyclic aliphatic hydrocarbon or a mixture thereof, in combination with a codiluent, that is orthophosphoric acid
Syntheses and UV/Vis-spectroscopic properties of hydrophilic 2-, 3-, and 4-pyridyl-substituted solvatochromic and halochromic pyridinium N-phenolate betaine dyes as new empirical solvent polarity indicators
Reichardt, Christian,Che, Daqing,Heckenkemper, Guido,Schaefer, Gerhard
, p. 2343 - 2361 (2007/10/03)
Syntheses and negative solvatochromism of nine new hydrophilic 2-, 3-, and 4-pyridyl-substituted pyridinium N-phenolate betaine dyes 3-11 are described. These were produced in order to obtain zwitterionic dyes better soluble in water and other aqueous media (such as binary water/solvent mixtures, aqueous ionophore solutions) than the rather hydrophobic standard betaine dyes 1 and 2, which have been used to establish an empirical scale of solvent polarity, called the ET(30) scale. Betaine dye 8, in which three of the peripheral phenyl groups of 1 are replaced by two 3-pyridyl rings and one 4-pyridyl ring, proved to be particularly suitable for the determination of ET(30) values in aqueous media. Wiley-VCH Verlag GmbH, 2001.