196959-51-0

Basic information

• Product Name: [2-(4-Chloro-phenyl)-6-methoxy-imidazo[1,2-a]pyridin-3-yl]-hydroxy-acetic acid ethyl ester
• Synonyms: [2-(4-Chloro-phenyl)-6-methoxy-imidazo[1,2-a]pyridin-3-yl]-hydroxy-acetic acid ethyl ester
• CAS NO: 196959-51-0
• Molecular Weight: 360.797
• Mol File: 196959-51-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-(4-Chloro-phenyl)-6-methoxy-imidazo[1,2-a]pyridin-3-yl]-hydroxy-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(4-Chloro-phenyl)-6-methoxy-imidazo[1,2-a]pyridin-3-yl]-hydroxy-acetic acid ethyl ester(196959-51-0)
• EPA Substance Registry System: [2-(4-Chloro-phenyl)-6-methoxy-imidazo[1,2-a]pyridin-3-yl]-hydroxy-acetic acid ethyl ester(196959-51-0)

Safety Data

• Hazardous Substances Data: 196959-51-0(Hazardous Substances Data)

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 196959-50-9 2-(4-Chlorophenyl)-6-methoxyimidazo[1,2-a]pyridine 

Relevant articles and documents

Imidazo[l,2-b]pyridazines. XXIII Some 5-Deaza Analogues. Syntheses of Some 2- Aryl-6-(chloro, methoxy or unsubstituted)-3-(variously substituted)imidazo[l,2-a]pyridines and Their Affinity for Central and Mitochondrial Benzodiazepine Receptors

The syntheses of ethyl {2′-aryl-6′-(chloro, methoxy and unsubstituted)imidazo[l,2-a]pyridin-3′-yl}-2-(acylamino, acetoxy and hydroxy)acetates, 3-benzamidomethyl-2-benzoyl-6-(chloro and methoxy)imidazo[l,2-a]pyridines, 3-amino-6-chloro-2-phenylimidazo[l,2-a]pyridine and ethyl 2-(2′-phenylimidazo[l,2-a]pyridin-3′-yl)acetate are reported. The ability of these compounds to displace [3H]diazepam from central and mitochondrial (peripheral-type) benzodiazepine receptors has been examined. Ethyl 2-benzamido-2-{6′-chloro-2′-(4″-chlorophenyl)imidazo[l,2-a] pyridin-3′-yl}acetate (21) was selective for peripheral-type receptors (IC50 13 nM) but none bound strongly to central receptors.