197020-64-7

Upstream product

• 100-42-5 styrene 
• 150884-56-3 N-tert-butyloxycarbonyl-3-(4-cyanophenyl)oxaziridine 
• 462100-44-3 oxaziridine-2,3,3-tricarboxylic acid 2-tert-butyl ester 3,3-diethyl ester 
• 20989-17-7 Phenylglycinol 
• 102089-74-7 tert-butyl 2-hydroxy-1-phenylethylcarbamate 
• 7568-93-6 2-Amino-1-phenylethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 67341-07-5 tert-butyl N-(2-hydroxy-2-phenylethyl)carbamate 

Downstream Products

• 182921-04-6 tert-butyl (2,2-diphenylethyl)carbamate 
• 7693-77-8 5-phenyloxazolidin-2-one 
• 113525-79-4 2-Oxo-5-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Heteroatom transfer to alkenes by N-protected-oxaziridines: New reaction pathways and products

N-Alkoxycarbonyl- and N-carboxamido-oxaziridines are shown to react with aromatic alkenes to give epoxide, aziridine or hydro-oxidation products, in ratios depending on the oxaziridine structure. Chiral oxaziridines can effect epoxidation and hydro-oxidation with promising levels of asymmetric induction.

Method for preparing beta arylamine

The invention discloses a method for preparing beta arylamine. The method includes mixing an aziridine compound, halogenated aromatic hydrocarbon, an oxidizing agent, a reducing agent and an organic solvent to obtain a mixed solution and obtaining the beta arylamine after reaction. The oxidizing agent is at least one of a mixture of nickel iodide and bipyridine, a mixture of nickel chloride dimethoxyethane and bipyridine and 2,2'-bipyridinium nickel iodide. The reducing agent is at least one of zinc powder, manganese powder, iron powder, cobalt powder, titanium powder, calcium powder and tetrakis(dimethylamino)ethylene. The halogenated aromatic hydrocarbon is at least one of the chlorinated aromatic hydrocarbon, the brominated aromatic hydrocarbon and aryl iodide. An organometallic reagentis not required, the preparation process is simple and reliable and high in yield, and the aziridine compound is wide in selection range.

Enantioselective synthesis of β-hydroxy amines and aziridines using asymmetric transfer hydrogenation of α-amino ketones

Enantioselective transfer hydrogenation of α-amino ketones is an effective method for the asymmetric synthesis of β-hydroxy amines and aziridines.

A Convenient One-Pot Conversion of N-Boc-β-Aminoalcohols into N-Boc-Aziridines

This paper describes an efficient single step transformation of chiral N-protected β-amino alcohols into appropriate aziridines.