150884-56-3

Basic information

• Product Name: N-BOC-3-(4-CYANOPHENYL)OXAZIRIDINE
• Synonyms: N-BOC-3-(4-CYANOPHENYL)OXAZIRIDINE;N-BOC-3-(4-CYANOPHENYL)OXAZIRIDINE, 98+%;tert-butyl 3-(4-cyanophenyl)oxaziridine-2-carboxylate
• CAS NO: 150884-56-3
• Molecular Formula: C₁₃H₁₄N₂O₃
• Molecular Weight: 246.26
• Mol File: 150884-56-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 57-63 °C
• Boiling Point: 389.26°C (rough estimate)
• Flash Point: 159.8°C
• Appearance: White to very slightly beige/Crystalline Powder
• Density: 1.1855 (rough estimate)
• Vapor Pressure: 8.5E-05mmHg at 25°C
• Refractive Index: 1.6450 (estimate)
• Storage Temp.: -20°C
• PKA: -5.46±0.40(Predicted)
• CAS DataBase Reference: N-BOC-3-(4-CYANOPHENYL)OXAZIRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BOC-3-(4-CYANOPHENYL)OXAZIRIDINE(150884-56-3)
• EPA Substance Registry System: N-BOC-3-(4-CYANOPHENYL)OXAZIRIDINE(150884-56-3)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 150884-56-3(Hazardous Substances Data)

Usage

Chemical Properties

white to very slightly beige crystalline powder

InChI:InChI=1/C13H14N2O3/c1-13(2,3)17-12(16)15-11(18-15)10-6-4-9(8-14)5-7-10/h4-7,11H,1-3H3/t11-,15?/m1/s1

Upstream product

• 105-07-7 4-cyanobenzaldehyde 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 150884-51-8 1,1-dimethylethyl N-[(4-cyanophenyl)methylen]carbamate 
• 68014-21-1 triphenyl(t-butoxycarbonylimino)phosphorane 

Downstream Products

• 138371-45-6 2-N-(tert-butoxycarbonyl)amino-1-phenyl-1-propanone 
• 57463-33-9 L-N-(tert-butoxycarbonylamino)valine 
• 188777-47-1 N-benzyl-N-(tert-butoxycarbonylamino)-L-isoleucine 
• 336850-32-9 (S)-1-(tert-butoxycarbonyl)-2-[α-(benzofuran-2-yl)-(4-chlorophenyl)methyl]hydrazine 
• 336850-33-0 (R)-1-(tert-butoxycarbonyl)-2-[α-(benzofuran-2-yl)-(4-chlorophenyl)methyl]hydrazine 
• 59255-58-2 tert-butyl butylcarbamate 
• 78348-96-6 4-(1-Hydroxy-pentyl)-benzonitrile 
• 18437-68-8 tert-butyl N-(4-methoxyphenyl)carbamate 
• 71872-03-2 tert-Butyl-carbamic acid tert-butyl ester 
• 134953-64-3 tert-butyl sec-butylcarbamate 
• 38267-76-4 tert-butyl N-ethylcarbamate 
• 3712-40-1 tert-butyl cyclohexylcarbamate 
• 3422-01-3 tert-butyl phenylcarbamate 
• 1099740-13-2 C₁₉H₂₀N₂O₂ 

Relevant articles and documents

PYRAZOLE AMIDE DERIVATIVE

The present invention relates to a novel compound having a function of inhibiting RORγ activity. The present invention also relates to pharmaceutical composition comprising the compound, a use of the compound in treating or preventing autoimmune diseases, inflammatory diseases, metabolic diseases, or cancer diseases.

Electrophilic Amination: Preparation and Use of N-Boc-3-(4-cyanophenyl)oxaziridine, a New Reagent That Transfers a N-Boc Group to N- and C-Nucleophiles

We describe the preparation of the title compound 2b via aza-Wittig reaction of N-Boc-triphenyliminophosphorane (6) with 4-cyanobenzaldehyde followed by Oxone oxidation of the resulting imine 5b.Oxaziridine 2b is a stable, crystalline solid, which transfers under mild conditions its N-Boc fragment to primary and secondary amines (to give Nβ-Boc-hydrazines) and enolates (to give N-Boc-amino drivatives).