197219-26-4Relevant academic research and scientific papers
SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS
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Page/Page column 134, (2015/04/15)
In one aspect, the present invention provides novel derivatives of Δ12-PGJ3 and modular synthetic pathways to obtaining Δ12-PGJ3 and derivatives thereof. In some aspects, the present derivatives of Δ12-PGJ3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.
Synthesis of phosphorylcholines possessing 5,6- or 14,15-epoxyisoprostane A2 at sn-2 position
Acharya, Hukum P.,Kobayashi, Yuichi
, p. 8435 - 8438 (2007/10/03)
Use of the PMBOCH2 group (PMB: p-MeOC6H 4CH2) as a substitute of CO2H provided high level of reproducibility and efficiency in construction of the full structure of 5,6-epoxyisoprostane A2.
Total synthesis of (±)-stemonamide and (±)-isostemonamide
Kende, Andrew S,Martin Hernando, Jose I,Milbank, Jared B.J
, p. 61 - 74 (2007/10/03)
Two different approaches to the alkaloids stemonamide and isostemonamide using N-acyliminium chemistry are described. The approach using an aldol spirocyclization to construct the second contiguous spirocenter was successful. The total synthesis of these
The biomimetic construction of fused cyclic polyethers
Hayashi, Nobuyuki,Fujiwara, Kenshu,Murai, Akio
, p. 12425 - 12468 (2007/10/03)
The formation of fused cyclic ethers by biomimetic synthesis was demonstrated. The one-pot successive ring-expansion reactions of bromo diepoxides were investigated by regarding the epoxy groups as the nucleophiles for the intramolecular cationic carbons to obtain the fused cyclic ethers.
