131375-65-0

Upstream product

• 131375-64-9 ethyl 7-(4-methoxyphenylmethoxy)-hept-2-enoate 
• 197219-26-4 7-(4-methoxybenzyloxy)-2-heptyn-1-ol 
• 286440-96-8 1-[(4-bromobutoxy)methyl]-4-methoxy benzene 
• 111-29-5 1 ,5-pentanediol 
• 131375-63-8 5-(4-methoxybenzyloxy)-1-pentanol 
• 131375-69-4 5-((4-methoxybenzyl)oxy)pentanal 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 928-90-5 5-hexyl-1-ol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 123186-35-6 1-[(hex-5-yn-1-yloxy)methyl]-4-methoxybenzene 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 197219-27-5 (2E)-1-(tert-butyldiphenylsilyloxy)-7-(4-methoxybenzyloxy)-2-heptene 
• 865302-35-8 (3R,4R)-(+)-2E-2-[(2R,3R)-2,3-epoxy-7-oxohept-1-enyl]-4-[(1,1-dimethylethyl)diphenylsilyloxy]-3-(2Z-octenyl)-cyclopentanone 
• 865302-34-7 (3R,4R)-(+)-2E-2-[(2R,3R)-2,3-epoxy-7-hydroxyhept-1-enyl]-4-[(1,1-dimethylethyl)diphenylsilyloxy]-3-(2Z-octenyl)-cyclopentanone 
• 865302-36-9 (2R,3R)-3-Z-[(4R,5R)-5-(2Z-octenyl)-2-oxo-4-[(1,1-dimethylethyl)diphenylsilyloxy]cyclopentylidenemethyl]oxirane-2-butanoic acid 
• 865302-33-6 (3R,4R)-(+)-2E-2-[(2R,3R)-2,3-epoxy-7-(4-methoxyphenylmethoxy)hept-1-enyl]-4-[(1,1-dimethylethyl)diphenylsilyloxy]-3-(2Z-octenyl)-cyclopentanone 
• 865302-32-5 (4R,5R)-(+)-2-[(1,1-dimethylethyl)dimethylsilyloxy]-4-[(1,1-dimethylethyl)diphenylsilyloxy]-5-(2Z-octenyl)-α-[(1R,2R)-1,2-epoxy-6-(4-methoxyphenylmethoxy)hexyl]cyclopent-2-enemethanol 
• 865302-38-1 C₆₀H₉₆NO₁₁PSi 
• 884345-52-2 (2R,3R)-7-(4-methoxybenzyloxy)-2,3-epoxy-1-iodoheptane 
• 884345-53-3 (R)-7-(4-methoxybenzyloxy)-3-triethylsilyloxyhept-1-ene 
• 131375-66-1 8-p-methoxybenzyloxy-1,1'-dibromoocta-1,3-diene 
• 131375-67-2 8-p-methoxybenzyloxy-(E)-3-octen-1-yne 
• 197219-29-7 (5E)-7-(tert-butyldiphenylsilyloxy)-5-hepten-1-ol 
• 197219-30-0 (2E)-7-bromo-1-(tert-butyldiphenylsilyloxy)-2-heptene 

Relevant academic research and scientific papers

Some limitations of an approach to the assembly of bryostatins by ring-closing metathesis

Preliminary studies into the use of ring-closing metathesis (RCM) in a convergent approach for the total synthesis of bryostatins are described. An ester that would have provided an advanced intermediate for a synthesis of a 20-deoxybryostatin by a RCM wa

Total synthesis of the epoxy isoprostane phospholipids PEIPC and PECPC

(Chemical Equation Presented) A total synthesis of the naturally occurring hydroxy ketone PEIPC 1, a compound that plays a role in endothelial activation in atherosclerosis, has been completed via a triply convergent preparation of a protected EI derivative 13 from 3,5-diacetoxycyclopentene 7, pentane-1,5-diol, and vinyllithium, using Sharpless epoxidation and enzymatic resolution as key steps. Final coupling with lyso-PC 16 and silyl group deprotection gave PECPC 2 and PEIPC 1, which showed the same activity as natural PECPC and PEIPC.

Chemoenzymatic total synthesis of the phytotoxic lactone herbarumin III

Asymmetric total synthesis of phytotoxic nonenolide herbarumin III was accomplished by a chemoenzymatic approach. The main highlight of the synthesis was to fix the hydroxyl stereocenters (C7 and C9) by lipase catalyzed irreversible transesterification.

Synthesis of phosphorylcholines possessing 5,6- or 14,15-epoxyisoprostane A2 at sn-2 position

Use of the PMBOCH2 group (PMB: p-MeOC6H 4CH2) as a substitute of CO2H provided high level of reproducibility and efficiency in construction of the full structure of 5,6-epoxyisoprostane A2.

The biomimetic construction of fused cyclic polyethers

The formation of fused cyclic ethers by biomimetic synthesis was demonstrated. The one-pot successive ring-expansion reactions of bromo diepoxides were investigated by regarding the epoxy groups as the nucleophiles for the intramolecular cationic carbons to obtain the fused cyclic ethers.

Synthesis of a Novel Acetylenic Ester, Methyl (E)-5-Octadecen-7,9-diynoate

We, herein, report synthesis of methyl ester of (E)-5-octadecen-7,9-diynoic acid, one of the novel acetylenic fatty acids of Paramacrolobium caeruleum root bark with unique biological activity, by coupling synthesized C1 to C8 fragment with 1-decyne.