197230-29-8

Upstream product

• 197230-08-3 4-benzyl-5-ethyl-2-methoxy-6-methyl-3-pivaloylaminopyridine 
• 100-39-0 benzyl bromide 
• 197229-98-4 5-ethyl-2-methoxy-6-methyl-3-pivaloylaminopyridine 
• 100-52-7 benzaldehyde 
• 139393-95-6 2-chloro-5-ethyl-6-methyl-3-nitropyridine 
• 139394-01-7 3-Amino-5-ethyl-2-methoxy-6-methylpyridine 
• 139394-00-6 2-methoxy-3-nitro-5-ethyl-6-methylpyridine 
• 143745-97-5 5-ethyl-6-methylpyridin-2(1H)-one 
• 107-87-9 2-Pentanone 
• 143745-99-7 2-ethyl-3-oxobutanal sodium salt 
• 139393-81-0 5-ethyl-6-methyl-3-nitro-2(1H)-pyridinone 
• 136562-04-4 3-cyano-5-ethyl-6-methylpyridin-2(1H)-one 

Relevant academic research and scientific papers

4-Benzyl- and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones, a new family of potent anti-HIV agents: Optimization and in vitro evaluation against clinically important HIV mutant strains

The 4-benzyl and 4-benzoyl-3-dimethylaminopyridinones 13 and 14 are representatives of a new class of highly potent non nucleoside type inhibitors of HIV-1 reverse transcriptase. To conduct SAR studies on these two lead compounds, 102 new analogues were p

Studies towards 4-C-alkylation of pyridin-2(1H)-one derivatives.

In order to obtain 4-C-alkylated pyridin-2(1H)-ones, two strategies were studied: nucleophilic substitution of 4-chloro-3-nitropyridinone derivatives which essentially failed and lithiations of 2-methoxy-3-pivaloylaminopyridines which gave the expected products.