197238-39-4

Basic information

• Product Name: 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid
• Synonyms: 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid
• CAS NO: 197238-39-4
• Molecular Weight: 295.249
• Mol File: 197238-39-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid(197238-39-4)
• EPA Substance Registry System: 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid(197238-39-4)

Safety Data

• Hazardous Substances Data: 197238-39-4(Hazardous Substances Data)

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 189256-18-6 2-(4-Oxo-pentanoyloxymethyl)-benzoic acid 

Downstream Products

• 197238-45-2 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 
• 224052-17-9 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-ylmethyl ester 
• 224052-22-6 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-3-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxy]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-ylmethyl ester 
• 224052-21-5 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3R,4R,5R)-3-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxy]-5-[4-(4-methoxy-benzoylamino)-2-oxo-2H-pyrimidin-1-yl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-ylmethyl ester 
• 224052-20-4 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3R,4R,5R)-3-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxy]-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-ylmethyl ester 
• 197238-46-3 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3S,5R)-3-[(2-cyano-ethoxy)-diisopropylamino-phosphanyloxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester 
• 197238-44-1 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3R,4R,5R)-3-hydroxy-5-(2-isobutyrylamino-6-oxo-1,6-dihydro-purin-9-yl)-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-ylmethyl ester 
• 224052-18-0 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3R,4R,5R)-3-hydroxy-5-[4-(4-methoxy-benzoylamino)-2-oxo-2H-pyrimidin-1-yl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-ylmethyl ester 
• 224052-19-1 5-Nitro-2-(4-oxo-pentanoyloxymethyl)-benzoic acid (2R,3R,4R,5R)-5-(6-benzoylamino-purin-9-yl)-3-hydroxy-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-2-ylmethyl ester 

Relevant articles and documents

Oligonucleotide synthesis by the use of a 2-(levulinyloxymethyl)-5-nitrobenzoyl group as the novel base-labile protecting group for the 5'-hydroxyl groups of ribonucleoside and 2'-deoxyribonucleoside 3'-phosphoramidites

A novel 2-(levulinyloxymethyl)-5-nitrobenzoyl (LMNBz) protecting group for the 5' position of nucleoside 3'-phosphoramidites was successfully applied to the solid-phase synthesis of both an oligodeoxyribonucleotide (TpTpT and TpTpTpT) and an octaribonucleotide in combination with a 2'-O-Thp protecting group (UpCpApGpUpUpGpG). The LMNBz group was simply unmasked due to its base-labile property by a two-step procedure, i.e., treatments with 0.5 M hydrazine hydrate in 1:4 acetic acid - pyridine, and then with 0.5 M imidazole in acetonitrile.