197316-13-5Relevant academic research and scientific papers
A New Asymmetric Synthesis of Tricarbonylchromium Complexes of ortho-Substituted Benzaldehydes
Kuendig, E. Peter,Liu, Ronggang,Ripa, Alberto
, p. 2657 - 2660 (1992)
ortho-Substituted complexes are obtained via nucleophilic addition of alkyl- and aryllithium reagents to a complex followed by endo-hydride abstraction with triphenylmethyl cation.This sequence, when carried out with a complex affords substituted derivatives (Me, Bu, Ph, vinyl) with high (>/= 97percent) diastereoselectivity and, after hydrolysis, ortho-substituted ((S)-1) complexes of high enantiomeric purity.
