19734-02-2

Basic information

• Product Name: 1-(2-hydroxyphenyl)pyrrolidin-2-one
• Synonyms: 1-(2-hydroxyphenyl)pyrrolidin-2-one;2-pyrrolidinone, 1-(2-hydroxyphenyl)-;1-(2-hydroxyphenyl)-2-pyrrolidinone;1-(2-hydroxyphenyl)-2-pyrrolidone;A1831/0077214;ZINC00069447
• CAS NO: 19734-02-2
• Molecular Formula: C₁₀H₁₁NO₂
• Molecular Weight: 177.19984
• Mol File: 19734-02-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(2-hydroxyphenyl)pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-hydroxyphenyl)pyrrolidin-2-one(19734-02-2)
• EPA Substance Registry System: 1-(2-hydroxyphenyl)pyrrolidin-2-one(19734-02-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 19734-02-2(Hazardous Substances Data)

Usage

General Description

1-(2-hydroxyphenyl)pyrrolidin-2-one, also known as phenylpiracetam, is a synthetic chemical compound derived from the neurotransmitter gamma-aminobutyric acid (GABA). It is classified as a nootropic, or "smart drug," and is believed to enhance cognitive function, memory, and learning. Phenylpiracetam is also thought to have stimulating and psychostimulant effects, making it potentially useful for improving focus and concentration. The compound has been studied for its potential therapeutic applications in treating cognitive impairments and neurological disorders, although more research is needed to fully understand its mechanisms of action and potential risks.

Upstream product

• 96-48-0 4-butanolide 
• 95-55-6 2-amino-phenol 
• 533-58-4 2-Iodophenol 
• 883244-95-9 cyclopropanecarboxylic acid (2-hydroxyphenyl)amide 
• 142523-69-1 1-benzyloxy-2-iodobenzene 

Downstream Products

• 857763-87-2 1-(2-methoxy-3-nitro-phenyl)-pyrrolidin-2-one 
• 23196-06-7 1-(2-methoxyphenyl)pyrrolidin-2-one 

Relevant articles and documents

METHOD FOR PRODUCING AN ARENE WITH AN AROMATIC C-N BOND ORTHO TO AN AROMATIC C-O BOND

A method for producing an arene with an aromatic C—N bond ortho to an aromatic C—O bond from a hydroxy arene comprising said aromatic C—O bond is provided. This method comprising the steps a) ortho-oxygenating the hydroxy arene to produce an ortho-quinone, b) condensating the ortho-quinone with a nitrogen nucleophile to generate a compound of Formula (IVa) or (IVb), and c) allowing 1,5-hydrogen atom shift of the compound of Formula (IVa) or (IVb), thereby producing arenes with a C—N bond ortho to a C—O bond of Formula (Va) and (Vb), respectively:

Synthesis of a new family of N-aryl lactams active on chemesthesis and taste

A new class of synthetic compounds with chemesthetic activity has been identified. They have been designed ex-novo by structural similarity with known cooling compounds such as menthol, icilin and cyclic ketoenamines. 19 new derivatives have been obtained