197365-66-5

Upstream product

• 63700-05-0 1,2;5,6-dianhydro-3,4-O-isopropylidene-D-mannitol 
• 98-88-4 benzoyl chloride 
• 197365-65-4 (5R,6R,7R,8R)-2,11-dimethyl-5,8-dihydroxy-6,7-isopropylidenedioxydodeca-1,11-diene 

Downstream Products

• 405556-17-4 (1R,2R)-2-benzoyloxy-5-methylenecyclohexanol 
• 405556-18-5 (3R,4R)-3-hydroxy-2-benzoyloxycyclohexanone 
• 405556-16-3 (2R)-2-benzoyloxy-5-methylhex-5-enal 
• 394739-02-7 C₂₈H₃₄O₆ 
• 405556-15-2 (5R,6R,7R,8R)-2,11-dimethyl-5,8-bis(benzoyloxy)-6,7-dihydroxydodeca-1,11-diene 

Relevant academic research and scientific papers

A new and efficient route to derivatives of (R)-4-hydroxycyclohex-2-enone

A new and efficient route has been developed to four derivatives of (R)-4-hydroxycyclohex-2-enone (7-10) from one intermediate, 6. These derivatives are useful chiral building blocks in the synthesis of natural products and in asymmetric reactions. The key step is a stereoselective intramolecular ene reaction with 4 A MS as the Lewis acid and catalyst.

Pd-catalyzed asymmetric allylation with a novel C2-symmetric bisphosphinite ligand: 3R,3′R-bis(diphenylphosphinoxy)-6,6,6′,6′-tetramethyl-2S, 2′S-di-4H-pyran

A novel C2-symmetric chiral bisphosphinite ligand, 3R,3′R-bis(diphenylphosphinoxy)-6,6,6′,6′-tetramethyl-2S, 2′S-di-4H-pyran, was synthesized from D-mannitol and examined for palladium-catalyzed asymmetric allylic substitution. Under the optimized conditions, the allylation product can be obtained in up to 91.2% ee.