405556-15-2Relevant academic research and scientific papers
A new and efficient route to derivatives of (R)-4-hydroxycyclohex-2-enone
Yu,Zhang,Wang
, p. 2958 - 2961 (2007/10/03)
A new and efficient route has been developed to four derivatives of (R)-4-hydroxycyclohex-2-enone (7-10) from one intermediate, 6. These derivatives are useful chiral building blocks in the synthesis of natural products and in asymmetric reactions. The key step is a stereoselective intramolecular ene reaction with 4 A MS as the Lewis acid and catalyst.
