19737-63-4

Upstream product

• 98977-36-7 3-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 578-57-4 2-bromoanisole 
• 5958-01-0 3-(2-methoxyphenyl)pyridine 
• 1120-90-7 3-iodopyridine 
• 5720-06-9 2-Methoxyphenylboronic acid 

Downstream Products

• 1602923-79-4 1,1,1-trifluoro-3-[3-(2-methoxy-phenyl)-piperidin-1-yl]-propan-2-ol 
• 1602922-43-9 (4-chlorophenyl)-carbamic acid 2,2,2-trifluoro-1-[3-(2-methoxyphenyl)-piperidin-1-ylmethyl]-ethyl ester 
• 1282042-15-2 C₂₂H₂₄N₄O₂ 
• 79412-37-6 2-(1-Propyl-piperidin-3-yl)-phenol; hydrobromide 

Relevant academic research and scientific papers

TRIAZACYCLODODECANSULFONAMIDE ("TCD")-BASED PROTEIN SECRETION INHIBITORS

Provided herein are triazacyclododecansulfonamide ("TCD")-based protein secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same. For example, provided herein are compounds of Formula (I) and pharmaceutically acceptable salts and compositions including the same. The compounds disclosed herein may be used, for example, in the treatment of diseases including inflammation and/or cancer.

PIPERIDINE AND AZEPINE DERIVATIVES AS PROKINETICIN RECEPTOR MODULATORS

The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof (Formula (I)) in which m, X, R1, R2, R3 and R5 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.