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**1H-Xanthen-1-one, 2,3,4,9-tetrahydro-9-(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-**, also referred to as **9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one**, is a tetrahydroxanthenone derivative synthesized via reactions involving dimedone and hydroxyarylaldehydes. It features a xanthene core fused with a cyclohexenone moiety, exhibiting dimerization in its crystalline form (space group *P21/c*). 1H-Xanthen-1-one, 2,3,4,9-tetrahydro-9-(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3 ,3-dimethyl- serves as a key intermediate in the synthesis of functionalized xanthenones and related heterocycles, with applications in photophysical studies and further derivatization. Its structure has been confirmed by X-ray crystallography, AIM, and NBO analyses. **Other names**: - 9-(2-Hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one - Tetrahydroxanthenone derivative (dimedone-based)

19744-87-7

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19744-87-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 19744-87-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,9,7,4 and 4 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 19744-87:
(7*1)+(6*9)+(5*7)+(4*4)+(3*4)+(2*8)+(1*7)=147
147 % 10 = 7
So 19744-87-7 is a valid CAS Registry Number.

19744-87-7Relevant academic research and scientific papers

A simple route for the synthesis of 3,3,3′,3′-tetramethyl-2,3, 3′,4′-tetrahydro-1H,1′H-[4,9′-bixanthene]-1, 1′(2′H,9′H)-dione and its derivatives catalyzed by Mn 2+ and other transition metal cations

Pesyan, Nader Noroozi,Golsanamloo, Vali,Ganbari, Shahnaz,?ahin, Ertan

, p. 4096 - 4099 (2012)

A simple and efficient unusual coupling reaction of 9-(2-hydroxy-4,4- dimethyl-6-oxocyclohex-1-en-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1- one and its derivatives was accomplished in the presence of Mn2+, Cu2+, Cd2+/

Synthesis, spectroscopic and photophysical studies of xanthene derivatives

Taghartapeh, Mohammad Ramezani,Noroozi Pesyan, Nader,Rashidnejad, Hamid,Khavasi, Hamid Reza,Soltani, Alireza

, p. 862 - 873 (2017)

We report on the experimental, crystal structure and computational investigation of a new class of xanthenes obtained by the reaction of salicylaldehyde and its derivatives with, 5,5-Dimethylcyclohexane-1,3-dione (Dimedone). The synthesized xanthenes were

Synthesis of novel tetrahydro[4,5]imidazo[2,1-b]-chromeno[4,3,2-de] quinazoline and benzothiazol-2-ylaminoxanthenone derivatives

Saeedi, Mina,Beheshtiha, Yahya S.,Heravi, Majid M.,Oskooie, Hossein A.

, p. 1831 - 1841 (2011)

Some novel tetrahydroquinazoline and xanthenone derivatives were synthesized from the reaction of dimedone and Schiff base in the presence of sulfamic acid in good yields. The Japan Institute of Heterocyclic Chemistry.

Investigation of 9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one: Crystal structure, AIM and NBO analysis

Udayakumar, Mani,Kothandapani, Jagatheeswaran,Ganesan, Subramaniapillai Selva,Venkataramanan, Natarajan S.,Madan Kumar, Shankar,Byrappa, Kullaiah,Thamotharan, Subbiah

, p. 510 - 518 (2017)

Single crystal X-ray analysis reveals that the 9-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, crystallizes in the centrosymmetric space group P21/c. In the crystal, molecules form as a dimer

2,4,6-Trichloro-1,3,5-triazine as an efficient catalyst for synthesis of benzopyran derivatives under solvent-free conditions

Zhang, Peng,Yu, Yong-Dong,Zhang, Zhan-Hui

, p. 4474 - 4479 (2008)

An efficient and convenient procedure has been developed for the synthesis of benzopyran derivatives by one-pot condensation of substituted salicyaldehydes and substituted 1,3-hexanediones in the presence of a catalytic amount of 2,4,6-trichloro-1,3,5-tri

Cellulose sulfuric acid: An efficient biodegradable and recyclable solid acid catalyst for the synthesis of 1-oxo-hexahydroxanthene

Kuarm, B. Suresh,Madhav, J. Venu,Laxmi, S. Vijaya,Rajitha,Reddy, Y. Thirupathi,Reddy, P. Narsimha,Crooks, Peter A.

, p. 1719 - 1724 (2011)

A series of 1-oxo-hexahydroxanthene derivatives was synthesized at room temperature in solid state from substituted salicylaldehydes and substituted 1,3-hexanediones in the presence of a catalytic amount of cellulose sulfuric acid. The results showed that

FeCl3·6H2O as a green and readily available catalyst for the synthesis of 1-oxo-hexahydroxanthenes by the condensation of salicylaldehydes with 1,3-diketones in aqueous media

Tajbakhsh, Mahmood,Heidary, Marzieh,Hosseinzadeh, Rahman,Amiri, Mohammadreza Azizi

, p. 141 - 145 (2016)

A facile and efficient method for the synthesis of 1-oxo-hexahydroxanthenes catalyzed by FeCl3·6H2O is described. The iron-catalyzed condensation of salicylaldehydes with cyclic 1,3-diketones afforded 1-oxo-hexahydroxanthene derivati

A clean synthesis of 1-oxo-hexahydroxanthene derivatives in aqueous media catalyzed by TEBA

Wang, Xiang-Shan,Shi, Da-Qing,Li, Yu-Ling,Chen, Hong,Wei, Xian-Yong,Zong, Zhi-Min

, p. 97 - 104 (2005)

A series of 1-oxo-1,2,3,4,9,10-hexahydroxanthene derivatives were synthesized from substituted salicylaldehydes and substituted 1,3-hexanedione in water at 90°C catalyzed by TEBA. The structure of the product was confirmed by X-ray analysis. Compared with other synthetic methods, this new method has the advantages of easier workup, milder reaction conditions, high yields (85 ~ 95%) and environmentally benign procedure.

An Efficient and Ecofriendly Three-Component Reaction for the Rapid Synthesis of 2-Amino-4 H -chromenes Catalyzed by a DABCO-Based Ionic Liquid

Li, Cheng-Bin,Li, Yu-Wei,Xu, Da-Zhen

, p. 3708 - 3714 (2018)

An efficient, economical, and green strategy for the construction of biologically relevant 2-amino-4 H -chromene scaffolds via a tandem Knoevenagel-Pinner cyclization-Michael reaction has been successfully developed. In the presence of DABCO-based ionic l

Efficient non-catalytic synthesis of substituted 2,3,4,9-tetrahydro-1H-xanthen-1-ones from salicylaldehydes and dimedone

Elinson, Michail N.,Sokolova, Olga O.,Nasybullin, Ruslan F.,Zaimovskaya, Tatiana A.,Egorov, Mikhail P.

, p. 19 - 20 (2015)

Thermally induced non-catalytic assembling of salicylaldehydes and dimedone in water or ethanol affords 9-(2-hydroxy-4,4-dimethyl- 6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-ones in 85-95% yields as a sequence of Knoevenagel and

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