197446-79-0

Upstream product

• 161949-46-8 3-chloro-2-(4-chlorophenyl)-5-(trifluoromethyl)pyridine 
• 69045-84-7 2,3-dichloro-5-trifluoromethylpyridine 
• 1679-18-1 4-Chlorophenylboronic acid 
• 161949-51-5 2-chloro-5-(3-chloro-5-trifluoromethyl-2-pyridyl)nitrobenzene 

Downstream Products

• 195304-19-9 2-chloro-5-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-4-fluoroaniline 
• 180153-43-9 2-(4-chloro-2-fluoro-5-hydroxyphenyl)-3-chloro-5-trifluoromethylpyridine 

Relevant academic research and scientific papers

Synthesis and herbicidal activity of phenylpyridines - A new lead

Novel phenylpyridines were synthesized based on molecular modeling oriented design by super-position of herbicidal phenyl-uracils, -indazoles, and diphenylethers. Their preparation follows Suzuki-type coupling conditions of reactive 2-chloro-pyridines with appropriate 2,5-substituted 4-chloro-phenyl boronic acids. Depending on the nature of substituents in the pyridine, and in particular the phenyl group, a large number of derivatives are readily accessible. Besides open-chain phenylpyridines also anellated compounds, such as pyridine-substituted 2H-1,4-benzothiazin-3(4H)-one or 3,4-dihydro-1H- quinolin-2-one, were prepared. Phenylpyridines act by inhibition of protoporphyrinogen-IX-oxidase. Their synthesis will be described in conjunction with structure-activity relationships. Phenylpyridines are highly active against many important broadleaf and grass weed species under pre- and - in particular - post-emergent conditions.

Process and intermediate products for preparing pyridyl-4-fluoroanilines

PCT No. PCT/EP97/01336 Sec. 371 Date Sep. 14, 1998 Sec. 102(e) Date Sep. 14, 1998 PCT Filed Mar. 17, 1997 PCT Pub. No. WO97/34872 PCT Pub. Date Sep. 25, 1997A process for preparing pyridyl-substituted N-phenylhydroxylamines by catalytic hydrogenation of t