1977-07-7 Usage
General Description
11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine is a chemical compound with the molecular formula C20H23N3. It belongs to the class of dibenzodiazepines and is structurally related to the drugs diazepam and lorazepam. 11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine has been studied for its potential pharmacological properties, including its effects on the central nervous system and its potential use as an anti-anxiety or sedative medication. It is a psychoactive compound that acts on the brain and has been the subject of research for its potential use in treating anxiety, depression, and other mental health conditions. However, it is important to note that the use of this chemical should only be under the supervision of a qualified healthcare professional, as its effects on the body and mind can be significant and potentially harmful if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 1977-07-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 7 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1977-07:
(6*1)+(5*9)+(4*7)+(3*7)+(2*0)+(1*7)=107
107 % 10 = 7
So 1977-07-7 is a valid CAS Registry Number.
InChI:InChI=1/C18H20N4/c1-21-10-12-22(13-11-21)18-14-6-2-3-7-15(14)19-16-8-4-5-9-17(16)20-18/h2-9,19H,10-13H2,1H3
1977-07-7Relevant articles and documents
Synthesis and evaluation of antitumor activity of dibenzodiazepine derivatives
Cao, Ke,Yan, Jianwei,Yan, Fulin,Yin, Tiantian
, p. 1111 - 1122 (2020/02/28)
Abstract: A series of dibenzodiazepine 2-position derivatives, bearing N-methylpiperazine at the C-11 position, were prepared by using a concise approach. Their inhibitory activities of tumor cell proliferation in vitro were tested in five cell lines, including breast cancer cell BCAP37, gastric cancer cell SGC7901, liver cancer cell HepG2, cervical cancer cell HeLa and acute promyelocytic leukemia cell HL-60. Several compounds showed efficient tumor activity with IC50 values down to 0.30?μM. These compounds are expected to be a new class of potential anticancer lead compounds. Graphic abstract: [Figure not available: see fulltext.]
Dibenzozepine compound and preparation method and application thereof
-
, (2018/10/11)
The invention discloses a dibenzozepine compound and a preparation method and application thereof. The structure of the dibenzozepine compound is as shown in the general formula 1 or general formula 2, wherein R1 is selected from methyl, hydrogen, chlorin
