197789-76-7Relevant academic research and scientific papers
An efficient method for the preparation of optically active 4-hydroxy-Δ2-isoxazolines
Wallace, Richard H.,Liu, Jinchu,Zong,Eddings, Alicia
, p. 6791 - 6794 (1997)
In this letter we report a method for the preparation of optically active 4-hydroxy-Δ2-isoxazolines. This methodology relies on the use of a camphorsultam substituted vinylboronic ester which upon nitrile oxide cycloaddition and oxidation affords the optically active 4-hydroxy-Δ2-isoxazolines in good yield.
