1978-33-2 Usage
Uses
Used in Pharmaceutical Industry:
2-Fluoro-3-methylaniline is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Fluoro-3-methylaniline serves as a key intermediate in the production of agrochemicals. Its incorporation into these compounds can enhance their effectiveness in pest control and crop protection, thereby supporting sustainable agriculture practices.
Both applications leverage the distinctive chemical properties of 2-Fluoro-3-methylaniline, harnessing its potential in creating innovative solutions for healthcare and agriculture.
Check Digit Verification of cas no
The CAS Registry Mumber 1978-33-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,7 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1978-33:
(6*1)+(5*9)+(4*7)+(3*8)+(2*3)+(1*3)=112
112 % 10 = 2
So 1978-33-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H8FN/c1-5-3-2-4-6(9)7(5)8/h2-4H,9H2,1H3
1978-33-2Relevant academic research and scientific papers
Industrial Cunninghamia lanceolata carbon supported FeO(OH) nanoparticles-catalyzed hydrogenation of nitroarenes
Fu, Lihua,Li, Dingzhong,Lu, Hao,Qiu, Renhua,Sun, Tulai,Xing, Chen,Yang, Tianbao
, (2022/01/11)
The development of green and efficient methods for hydrogenation of nitroarenes is still highly demanding in organic synthesis. Herein, we report an industrial Cunninghamia lanceolata carbon supported FeO(OH) nanoparticles process for the synthesis of aryl amines with good yields via hydrogenation of nitroarenes. Nine key anti-cancer drug intermediates were successfully achieved with protocol. And Osimertinib intermediate 4m can be smoothly synthesized at a 2.67 kg-scale with >99.5% HPLC purity. This protocol features cheap carbon source, highly catalytic activity, simple operation, kilogram-scalable and recyclable catalysts (eight times without observable losing activity).
