197855-65-5 Usage
Description
Z-FA-FMK is an irreversible inhibitor of cysteine proteases, including cathepsins B, L, and S, cruzain, and papain. It also inhibits effector caspases-2, -3, -6, and -7 (IC50 = 6-32 μM) without affecting the initiator caspases-8 and -10. Z-FA-FMK also modulates infection by certain bacteria, parasites, and viruses. It can be used both in cells and in vivo.
Check Digit Verification of cas no
The CAS Registry Mumber 197855-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,7,8,5 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 197855-65:
(8*1)+(7*9)+(6*7)+(5*8)+(4*5)+(3*5)+(2*6)+(1*5)=205
205 % 10 = 5
So 197855-65-5 is a valid CAS Registry Number.
197855-65-5Relevant articles and documents
α Amino fluoro ketones
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, (2008/06/13)
Novel α amino fluoro ketones, a method of their synthesis and a method for irreversibly inhibiting proteases is disclosed.
