197892-27-6

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 95766-36-2 H-A₂bu(Z)-OH 
• 47461-65-4 4-(((benzyloxy)carbonyl)amino)-2-((tert-butoxycarbonyl)amino)butanoic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 318514-25-9 (E)-6-benzyloxycarbonylamino-4-tert-butoxycarbonylamino-hex-2-enoic acid tert-butyl ester 

Relevant academic research and scientific papers

Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 1. The α-methyl-trans-lactam template

Mechanism-based inhibitors of human cytomegalovirus (HCMV) protease have been designed based on the pyrrolidine-5,5-trans-lactam ring system. New routes to the β-methyl-, desmethyl-, and α-methyl-pyrrolidine-5,5-trans-lactam templates have been developed

Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase

There are described according to the invention compounds of formula (I) (relative stereochemistry indicated), wherein R1, R2, R3 and X are as defined in the specification, together with processes for preparing them, compositions containing them and their use as pharmaceuticals. Compounds of formula (I) are indicated inter alia for the treatment of chronic bronchitis.