318514-25-9Relevant academic research and scientific papers
Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 1. The α-methyl-trans-lactam template
Borthwick,Angier,Crame,Exall,Haley,Hart,Mason,Pennell,Weingarten
, p. 4452 - 4464 (2007/10/03)
Mechanism-based inhibitors of human cytomegalovirus (HCMV) protease have been designed based on the pyrrolidine-5,5-trans-lactam ring system. New routes to the β-methyl-, desmethyl-, and α-methyl-pyrrolidine-5,5-trans-lactam templates have been developed
