198017-51-5

Basic information

• Product Name: ethyl 4-(3-ethylamino-6-phenyl-2-pyridyl)-1-piperazinocarboxylate
• Synonyms: ethyl 4-(3-ethylamino-6-phenyl-2-pyridyl)-1-piperazinocarboxylate
• CAS NO: 198017-51-5
• Molecular Weight: 354.452
• Mol File: 198017-51-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-(3-ethylamino-6-phenyl-2-pyridyl)-1-piperazinocarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(3-ethylamino-6-phenyl-2-pyridyl)-1-piperazinocarboxylate(198017-51-5)
• EPA Substance Registry System: ethyl 4-(3-ethylamino-6-phenyl-2-pyridyl)-1-piperazinocarboxylate(198017-51-5)

Safety Data

• Hazardous Substances Data: 198017-51-5(Hazardous Substances Data)

Upstream product

• 102266-15-9 2-amino-3-nitro-6-phenylpyridine 
• 198017-49-1 ethyl 4-(3-nitro-6-phenyl-2-pyridyl)-1-piperazinocarboxylate 
• 198017-46-8 ethyl (E)-4-(1-amino-2-nitroethene-1-yl)-1-piperazinocarboxylate 
• 187242-88-2 2-chloro-3-nitro-6-phenylpyridine 
• 120-43-4 4-ethoxycarbonylpiperazine 
• 75-07-0 acetaldehyde 
• 198017-50-4 ethyl 4-(3-amino-6-phenyl-2-pyridyl)-1-piperazinocarboxylate 

Downstream Products

• 198017-52-6 1-(3-ethylamino-6-phenyl-2-pyridyl)piperazine 

Relevant articles and documents

Synthesis of 6-Phenyl-Atevirdine

The synthesis of 6-phenyl-atevirdine (17), a lipophilic derivative of the potent HIV-1 reverse transcriptase inhibitor atevirdine (1), is described. The title compound was prepared from dithioacetale 2 via keteneaminal 4 and the nitropyridine derivative 10. Unexpectedly, no anti HIV activity was observed for the novel atevirdine derivative 17. The key intermediates 6, 8 and 10 could also be prepared from keteneaminal 18 via chloropyridines 22-24.