187242-88-2

Usage

Uses

Used in Pharmaceutical Industry:
2-chloro-3-nitro-6-phenylpyridine is utilized as a key intermediate in the synthesis of pharmaceuticals for its ability to be chemically modified to produce a range of medicinal compounds. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-chloro-3-nitro-6-phenylpyridine is employed as an intermediate in the production of pesticides and other crop protection agents, contributing to the development of effective solutions for agricultural challenges.
Used in Dyes and Pigments Manufacturing:
2-chloro-3-nitro-6-phenylpyridine is used as a building block in the creation of dyes and pigments, providing a foundation for the production of colorants used in various industries, such as textiles, plastics, and printing inks.
Used in Research and Development:
2-chloro-3-nitro-6-phenylpyridine is also valuable in research and development settings, where it can be explored for new applications, potential reactions, and as a model compound in chemical studies, furthering scientific understanding and innovation in the chemical and related industries.

Upstream product

• 16013-85-7 2,6-dicholoro-3-nitropyridine 
• 98-80-6 phenylboronic acid 
• 5467-74-3 4-Bromophenylboronic acid 
• 1430341-84-6 6-bromo-2-chloro-3-nitropyridine 
• 27048-04-0 2-amino-6-chloro-3-nitropyridine 
• 92138-35-7 6-chloro-3-nitro-1H-pyridin-2-one 
• 39258-93-0 3-nitro-6-phenylpyridin-2(1H)-one 
• 1131-80-2 (E)-3-(N,N-dimethylamino)-1-phenyl-2-propen-1-one 

Downstream Products

• 198017-49-1 ethyl 4-(3-nitro-6-phenyl-2-pyridyl)-1-piperazinocarboxylate 
• 1439394-30-5 tert-butyl(1-(4-((3-amino-6-phenylpyridin-2-yl)amino)phenyl)cyclobutyl)carbamate 
• 1313881-69-4 tert-butyl (1-(4-(2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl)cyclobutyl)carbamate 
• 1313881-70-7 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine 
• 1439394-28-1 tert-butyl (1-(4-((3-nitro-6-phenylpyridin-2-yl)amino)phenyl)cyclobutyl)carbamate 
• 198017-51-5 ethyl 4-(3-ethylamino-6-phenyl-2-pyridyl)-1-piperazinocarboxylate 
• 198017-50-4 ethyl 4-(3-amino-6-phenyl-2-pyridyl)-1-piperazinocarboxylate 
• 198017-52-6 1-(3-ethylamino-6-phenyl-2-pyridyl)piperazine 

Relevant academic research and scientific papers

Compound for organic electroluminescent device

The invention provides a compound for an organic electroluminescent device. The compound is characterized in that a structural formula of the compound is shown as a formula (I) in the description. Thecompound provided by the invention is applied to an org

PROCESS OF PREPARING 3-(3-(4-(1-AMINOCYCLOBUTYL)PHENYL)-5-PHENYL-3H-IMIDAZO[4,5-B]PYRIDIN-2-YL)PYRIDIN-2-AMINE

The present invention is directed to a processes for the synthesis of 3-(3-(4-(1-aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine:

Ortho-(Dimesitylboryl)phenylphosphines: Positive boryl effect in the palladium-catalyzed suzuki-miyaura coupling of 2-chloropyridines

Catalytic systems combining ortho-(dimesitylboryl) phenylphosphines and palladium precursors have been evaluated in the Suzuki-Miyaura couplings of chloro-N-heterocycles, in particular 2-chloro pyridines, with arylboronic acids. The Lewis basic character of the substrates does not interfere with the Lewis acidic site of the ligands, even for a substrate featuring free NH2 groups. The influence of several reaction parameters has been studied and the ortho-dimesitylboryl moiety was actually found to substantially enhance the catalytic performance. The role of this group has been examined using preformed phosphine-borane/Pd complexes and the formation of an original phosphine/h4-boratabutadiene complex has been identified as a possible deactivation pathway. Regioselective coupling of 2,6-dichloro-3-nitropyridine with phosphine-borane/Pd catalysts has also been explored, and sequential double cross-couplings were found to give a direct and efficient access to unsymmetrical 2,6-diarylpyridines.

Chemical Compounds

The invention is directed to novel azaindole and azaindazole carboxamide derivatives. Specifically, the invention is directed to compounds according to formula (I): where R1, R2, T1, T2 and T3 are defined below. These compounds are useful in the treatment of disorders associated with inappropriate IKK2 (also known as IKKβ) activity, in particular in the treatment and prevention of disorders mediated by IKK2 mechanisms including inflammatory and tissue repair disorders. Such disorders include rheumatoid arthritis, asthma, and COPD (chronic obstructive pulmonary disease).

Versatile synthesis of 6-substituted 8-deazapteridine-2,4-diamines. Formal total synthesis of 8,10-dideazaminopterin

A new synthesis of 4-amino-4-deoxy-8,10-dideazapteroic acid (11d) and 6-substituted and 5,6-anellated 8-deazapteridine-2,4-diamines, 10a, 10d, 25, is described. Starting from keteneaminals 1 or 12 and enaminones 4 or β-aminoketone 17 the title compounds can be prepared via functional group transformation of 2-amino-3-nitropyridines 5 or nicotinate 13a yielding 3-amino-α-picolinonitriles 9 which are cyclocondensed with guanidine.