198021-01-1 Usage
General Description
5,8-Dimethoxy-1,2,3,4-tetrhydroisoquinoline-3-carboxylic acid ethyl ester is a chemical compound with a complex structure that includes a tetracyclic isoquinoline ring system. It is an ethyl ester derivative of a carboxylic acid, and it contains two methoxy groups attached to the 5 and 8 positions of the isoquinoline ring. 5,8-Dimethoxy-1,2,3,4-tetrhydroisoquinoline-3-carboxylic acid ethyl ester has potential pharmacological activity and may be used as a starting material for the synthesis of other bioactive compounds. Its structure and properties make it an interesting molecule for research and development in the fields of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 198021-01-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,8,0,2 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 198021-01:
(8*1)+(7*9)+(6*8)+(5*0)+(4*2)+(3*1)+(2*0)+(1*1)=131
131 % 10 = 1
So 198021-01-1 is a valid CAS Registry Number.
InChI:InChI=1/C14H19NO4/c1-4-19-14(16)11-7-9-10(8-15-11)13(18-3)6-5-12(9)17-2/h5-6,11,15H,4,7-8H2,1-3H3
198021-01-1Relevant articles and documents
Synthesis of hexahydropyrazino[1,2-b]isoquinolines as simplified saframycin analogues
Nguyen Van, Tuyen,Claes, Pieter,De Kimpe, Norbert
supporting information, p. 69 - 74 (2014/01/06)
Various hexahydropyrazino[1,2-b]isoquinolines were synthesised as simplified saframycin analogues. Construction of this core proceeded through a tetrahydroisoquinoline synthesis followed by acylation/alkylation of the tetrahydroisoquinoline nitrogen and subsequent ring closure using various aliphatic and aromatic amines. The resulting piperazinones were reacted with LiAlH4 or LiAlH(OEt)3 to synthesise further analogues. Georg Thieme Verlag Stuttgart · New York.
Synthesis of ethyl N-(diphenyl)methyl-1,2,3,4- tetrahydroisoquinoline-3-carboxylates
Mash, Eugene A.,Williams, Lawrence J.,Pfeiffer, Steven S.
, p. 6977 - 6980 (2007/10/03)
A concise method for the synthesis of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives from α,α'-dibromo-o-xylenes via sequential C-alkylation and N-alkylation of a glycine anion is described.
