198022-19-4Relevant articles and documents
A contribution to the asymmetric synthesis of 3-amine β-lactams: The diastereoselective [2+2] cycloaddition reaction of chiral aminoketene equivalents with enolizable aldehyde-derived/mines
Palomo, Claudio,Aizpurua, Jesus M.,Legido, Marta,Mielgo, Antonia,Galarza, Regina
, p. 1432 - 1441 (2007/10/03)
N-[Bis(trimethylsilyl)methyl]imines 9 show unique chemical properties when compared with conventional imines. Their reaction with optically pure aminoketenes derived from dehydrochlorination of 14 and 15 affords the corresponding 3-amino-4-alkyl-β-lactams