198063-13-7

Basic information

• Product Name: 1-amino-8-trityloxy-3,6-dioxaoctane
• Synonyms: 1-amino-8-trityloxy-3,6-dioxaoctane
• CAS NO: 198063-13-7
• Molecular Weight: 391.51
• Mol File: 198063-13-7.mol

Chemical Properties

• CAS DataBase Reference: 1-amino-8-trityloxy-3,6-dioxaoctane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-amino-8-trityloxy-3,6-dioxaoctane(198063-13-7)
• EPA Substance Registry System: 1-amino-8-trityloxy-3,6-dioxaoctane(198063-13-7)

Safety Data

• Hazardous Substances Data: 198063-13-7(Hazardous Substances Data)

Upstream product

• 133699-10-2 10,10,10-Triphenyl-3,6,9-trioxadecyl-p-toluenesulfonate 
• 745048-13-9 [{2-[2-(2-azidoethoxy)ethoxy]ethoxy}(diphenyl)methyl]benzene 
• 76-83-5 trityl chloride 
• 133699-09-9 10,10,10-triphenyl-3,6,9-trioxadecan-1-ol 
• 146462-59-1 1-(methylsulfonyl)-10-(triphenylcarbinyl)-1,4,7,10-tetraoxadecane 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 77544-68-4 8-tosyloxy-3,6-dioxaoctanol 

Downstream Products

• 198063-14-8 5-Dimethylamino-naphthalene-1-sulfonic acid {2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethyl}-amide 
• 198063-16-0 Toluene-4-sulfonic acid 2-{2-[2-(5-dimethylamino-naphthalene-1-sulfonylamino)-ethoxy]-ethoxy}-ethyl ester 

Relevant articles and documents

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Synthesis and stability of two indomethacin prodrugs

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Synthesis of novel dansyl appended cyclodextrins. Self-inclusion and sensor properties

The synthesis of three dansyl appended cyclodextrin derivatives, differing in the spacer length between cyclodextrin and the dansyl moiety, is described. In compound 4 the fluorophore is directly attached to the cyclodextrin. Compound 5 contains an ethyl spacer and compound 6 a triethylene glycol spacer. These compounds are designed to detect neutral organic guest molecules like cyclohexanol and adamantanecarboxylic acid in water by fluorescence spectroscopy. At neutral pH none of the compounds is sensitive towards guest molecules. For compound 4 this is due to the fact that the dansyl group is located outside the cyclodextrin cavity. For compunds 5 and 6 the low sensitivity is the result of a strong self-inclusion of the dansyl group. Lowering the pH results in protonation of the dimethylamino group of the dansyl moiety, which makes the self-inclusion less favourable leading to a strongly increased response towards guests. This phenomenon allows the sensors to be switched on and off by lowering or increasing the pH of the solution. Compound 6 is able to detect adamantanecarboxylic acid at 5 × 10-7 mol-1 dm3 concentration at pH 1.