146462-59-1Relevant articles and documents
MACROCYCLIC COMPOUNDS FOR MODULATING IL-17
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, (2013/08/15)
The invention relates generally to macrocyclic compounds of formula I and their therapeutic use. More particularly, the invention relates to macrocyclic compounds that modulate the activity of IL-17 and/or are useful in the treatment of medical conditions
Tunable, dynamic and electrically stimulated lectin-carbohydrate recognition on a glycan-grafted conjugated polymer
Luo, Shyh-Chyang,Kantchev, Eric Assen B.,Zhu, Bo,Siang, Yuen Wee,Yu, Hsiao-Hua
, p. 6942 - 6944 (2012/08/29)
An electroactive platform for multivalent, reversible and electrically stimulated lectin-carbohydrate recognition based on mannose-functionalized conjugated polymer is reported and tuned by electrocopolymerization of mixture of tri(ethylene glycol)-functi
Synthesis and stability of two indomethacin prodrugs
Chandrasekaran, Shyamala,Al-Ghananeem, Abeer M.,Riggs, Robert M.,Crooks, Peter A.
, p. 1874 - 1879 (2007/10/03)
The purpose of this study was to synthesize and study the in vitro enzymatic and non-enzymatic hydrolysis of indomethacin-TEG ester and amide prodrugs. It was found that the ester conjugate 10 was comparatively stable between pH 3 and 6 (half-life >90 h),