198135-56-7

Basic information

• Product Name: 6-(4-methoxyphenyl)-5-methyl-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile
• Synonyms: 6-(4-methoxyphenyl)-5-methyl-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile
• CAS NO: 198135-56-7
• Molecular Weight: 287.339
• Mol File: 198135-56-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 6-(4-methoxyphenyl)-5-methyl-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-methoxyphenyl)-5-methyl-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile(198135-56-7)
• EPA Substance Registry System: 6-(4-methoxyphenyl)-5-methyl-4-(methylthio)-2-oxo-2H-pyran-3-carbonitrile(198135-56-7)

Safety Data

• Hazardous Substances Data: 198135-56-7(Hazardous Substances Data)

Upstream product

• 3490-92-4 methyl 2-cyano-3,3-bis(methylsulfanyl)acrylate 
• 121-97-1 4-Methoxypropiophenone 
• 17823-58-4 ethyl 2-cyano-3,3-di(methylsulfanyl)acrylate 

Downstream Products

• 1448901-09-4 6-isopropyl-4-(4-methoxyphenyl)-3-methyl-5-phenyl-2H-pyran-2-one 
• 1158797-23-9 C₁₉H₂₀N₂O₃ 

Relevant articles and documents

Regioselective synthesis of functionally congested biaryls through a novel C-C bond formation reaction

An expeditious synthesis of unsymmetrical biaryls functionalized with electron-withdrawing or -donating substituents is described and illustrated by the carbanion-induced ring transformation of 2H-pyran-2-ones with malononitrile in excellent yields.

A Metal-Free Approach for the Synthesis of 2-Tetralones via Carbanion-Induced Ring Transformation of 2 H -Pyran-2-ones

A metal-free, ultrasound-assisted approach for the synthesis of highly functionalized 2-tetralones in high yields is described. The process involves ring transformation of 2 H -pyran-2-ones with the spirocyclic ketone 1,4-cyclohexandione monoethylene keta

Arylanthranilodinitriles: A new biaryl class of antileishmanial agents

A series of anthranilodinitrile-based biaryls were synthesized and evaluated in vitro against extracellular promastigotes and intracellular amastigotes of Leishmania donovani. Among various screened compounds, a biaryl with trifluoromethyl group 5f showed