1982-37-2Relevant articles and documents
Stability of some phenothiazine free radicals.
Levy,Tozer,Tuck,Loveland
, p. 898 - 905 (2007/10/10)
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1982-37-2
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Basic information
- Product Name: METHDILAZINE (200 MG)
- Synonyms: METHDILAZINE (200 MG);10-((1-methyl-3-pyrrolidinyl)methyl)-phenothiazin;10-((1-methyl-3-pyrrolidinyl)methyl)-phenothiazine;10-[(1-Methyl-3-pyrrolidinyl)methyl]-10H-phenothiazine;10-[(1-Methyl-3-Pyrrolidinyl)methyl]phenothiazine;10H-Phenothiazine, 10-[(1-methyl-3-pyrrolidinyl)methyl]-;Dilosyn;Disyncram
- CAS NO:1982-37-2
- Molecular Formula: C18H20N2S
- Molecular Weight: 296.4298
- EINECS: 217-841-6
- Product Categories: N/A
- Mol File: 1982-37-2.mol
- Article Data: 2
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Chemical Properties
- Melting Point: 87-88℃
- Boiling Point: 430.4 ºC at 760 mmHg
- Flash Point: 214.1 ºC
- Appearance: /
- Density: 1.185
- Refractive Index: 1.6000 (estimate)
- Storage Temp.: N/A
- Solubility: N/A
- PKA: pKa 7.45 (Uncertain)
- CAS DataBase Reference: METHDILAZINE (200 MG)(CAS DataBase Reference)
- NIST Chemistry Reference: METHDILAZINE (200 MG)(1982-37-2)
- EPA Substance Registry System: METHDILAZINE (200 MG)(1982-37-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1982-37-2(Hazardous Substances Data)
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1982-37-2 Usage
Uses
Antipruritic.General Description
Different sources of media describe the General Description of 1982-37-2 differently. You can refer to the following data:1. Methdilazine, 10-[(1-methyl-3-pyrrolidinyl)methyl]phenothiazine (Tacaryl), is a light-tan crystallinepowder that has a characteristic odor and is practicallyinsoluble in water. Methdilazine, as the free base, isused in chewable tablets because its low solubility in watercontributes to its tastelessness. Some local anesthesia of thebuccal mucosa may be experienced if the tablet is chewedand not swallowed promptly.
2. Crystals.
Reactivity Profile
METHDILAZINE (200 MG) is sensitive to light. .Health Hazard
SYMPTOMS: Symptoms of exposure to METHDILAZINE (200 MG) may include drowsiness, hypotension, tachycardia, dryness of the mouth, nausea, nasal congestion, fever and tremors.Fire Hazard
Flash point data for METHDILAZINE (200 MG) are not available. METHDILAZINE (200 MG) is probably combustible.Check Digit Verification of cas no
The CAS Registry Mumber 1982-37-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,9,8 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.Calculate Digit Verification of CAS Registry Number 1982-37:
(6*1)+(5*9)+(4*8)+(3*2)+(2*3)+(1*7)=102
102 % 10 = 2
So 1982-37-2 is a valid CAS Registry Number.
InChI:InChI=1S/C18H20N2S/c1-19-11-10-14(12-19)13-20-15-6-2-4-8-17(15)21-18-9-5-3-7-16(18)20/h2-9,14H,10-13H2,1H3
1982-37-2Synthetic route
Conditions
| Conditions | Yield |
|---|---|
| With sodium amide |
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92-84-2
10H-phenothiazine
- (+-)-3-chloromethyl-1-methyl-pyrrolidine
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(+-)-3-chloromethyl-1-methyl-pyrrolidine
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1982-37-2
methdilazine
1982-37-2Upstream product
1982-37-2Downstream Products
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METHDILAZINE (200 MG)
