198205-99-1Relevant articles and documents
A convergent asymmetric synthesis of a growth hormone secretagogue
Zheng, Nan,Armstrong III, Joseph D.,Eng, Kan K.,Keller, Jennifer,Liu, Tom,Purick, Robert,Lynch, Joseph,Hartner, Frederick W.,Volante
, p. 3435 - 3446 (2003)
Described herein is a convergent asymmetric synthesis of growth hormone secretagogue (GHS) suitable for large-scale preparations. Key features include: (1) an improved method for α-iodination of a lactam; (2) a novel synthesis of a disubstituted urea usin