1983-99-9

Basic information

• Product Name: ethyl 4-isocyanobenzoate
• CAS NO: 1983-99-9
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.184
• Mol File: 1983-99-9.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: ethyl 4-isocyanobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-isocyanobenzoate(1983-99-9)
• EPA Substance Registry System: ethyl 4-isocyanobenzoate(1983-99-9)

Safety Data

• Hazardous Substances Data: 1983-99-9(Hazardous Substances Data)

Upstream product

• 150-13-0 4-amino-benzoic acid 
• 5422-63-9 N-(4-ethoxycarbonylphenyl)formamide 
• 64-18-6 formic acid 
• 94-09-7 p-aminoethylbenzoate 

Downstream Products

• 98434-02-7 4-carboxyphenyl isocyanide 

Relevant articles and documents

[Ph3C][B(C6F5)4]: A Highly Efficient Metal-Free Single-Component Initiator for the Helical-Sense-Selective Cationic Copolymerization of Chiral Aryl Isocyanides and Achiral Aryl Isocyanides

Commercially available [Ph3C][B(C6F5)4] served as a highly efficient metal-free and single-component initiator not only for the carbocationic polymerization of polar and bulky aryl isocyanides with extremely high activity up to 1.2×107 g of polymer/(molcat. h), but also for the helical-sense-selective polymerization of chiral aryl isocyanides and copolymerization with achiral aryl isocyanides to afford high-molecular-weight functional poly(aryl isocyanide)s with good solubility as well as AIE characteristics and/or a single-handed helical conformation.

TEMPO-Catalyzed Aerobic Oxidative Selenium Insertion Reaction: Synthesis of 3-Selenylindole Derivatives by Multicomponent Reaction of Isocyanides, Selenium Powder, Amines, and Indoles under Transition-Metal-Free Conditions

A novel and efficient approach for the selenium functionalization of indoles was developed with selenium powder as the selenium source, catalyzed by 2,2,6,6-tetramethylpiperidinooxy (TEMPO) and employing O2 as the green oxidant. This protocol provides a practical route for the synthesis of 3-selenylindole derivatives and has the advantages of readily available starting materials, mild reaction conditions, and a wide scope of substrates. Electron spin-resonance (ESR) studies reveal that the approach involves the formation of nitrogen-centered radicals and selenium radicals via oxidation of in situ generated selenoates.

Cobalt(II)-Catalyzed Isocyanide Insertion Reaction with Sulfonyl Azides in Alcohols: Synthesis of Sulfonyl Isoureas

A Co(II)-catalyzed isocyanide insertion reaction with sulfonyl azides in alcohols to form sulfonyl isoureas via nitrene intermediate has been developed. This protocol provides a new, environmentally friendly, and simple strategy for the synthesis of sulfonyl isourea derivatives by employing a range of substrates under mild conditions.