198344-47-7Relevant academic research and scientific papers
Resolution of pentafluorophenyl 2-phenylpropanoate using combinations of quasi-enantiomeric oxazolidin-2-ones
Shaye, Najla Al,Benoit, David M.,Chavda, Sameer,Coulbeck, Elliot,Dingjan, Marco,Eames, Jason,Yohannes, Yonas
experimental part, p. 413 - 438 (2011/06/17)
The kinetic, mutual and parallel resolution of a series of structurally related active esters derived from 2-phenylpropanoic acid using a combination of quasi-enantiomeric oxazolidin-2-ones is discussed.
Resolution of pentafluorophenyl esters using oxazolidin-2-ones
Al Shaye, Najla,Eames, Jason
scheme or table, p. 5892 - 5895 (2010/11/18)
A series of structurally related racemic pentafluorophenyl active esters were resolved using an equimolar amount of (S)-4-phenyloxazolidin-2-one. The levels of diastereocontrol were found to be excellent (80-96% de) at ～40% conversion.
Parallel kinetic resolution of racemic oxazolidinones using quasi-enantiomeric active esters
Boyd, Ewan,Coulbeck, Elliot,Coumbarides, Gregory S.,Chavda, Sameer,Dingjan, Marco,Eames, Jason,Flinn, Anthony,Motevalli, Majid,Northen, Julian,Yohannes, Yonas
, p. 2515 - 2530 (2008/03/15)
Racemic Evans' oxazolidinones were efficiently resolved using a combination of quasi-enantiomeric profens. The levels of stereocontrol were high, leading to products with predictable configurations.
Investigations into the parallel kinetic resolution of 2-phenylpropanoyl chloride using quasi-enantiomeric oxazolidinones
Chavda, Sameer,Coulbeck, Elliot,Coumbarides, Gregory S.,Dingjan, Marco,Eames, Jason,Ghilagaber, Stephanos,Yohannes, Yonas
, p. 3386 - 3399 (2007/10/03)
The resolution of 2-phenylpropanoyl chloride using an equimolar combination of quasi-enantiomeric oxazolidinones is discussed. The levels of diastereoselectivity were found to be dependent upon the structural nature of the metallated oxazolidinone, temperature and metal counter-ion.
