219951-25-4Relevant academic research and scientific papers
Resolution of pentafluorophenyl 2-phenylpropanoate using combinations of quasi-enantiomeric oxazolidin-2-ones
Shaye, Najla Al,Benoit, David M.,Chavda, Sameer,Coulbeck, Elliot,Dingjan, Marco,Eames, Jason,Yohannes, Yonas
experimental part, p. 413 - 438 (2011/06/17)
The kinetic, mutual and parallel resolution of a series of structurally related active esters derived from 2-phenylpropanoic acid using a combination of quasi-enantiomeric oxazolidin-2-ones is discussed.
A method for determining the enantiomeric purity of profens
Coulbeck, Elliot,Eames, Jason
body text, p. 635 - 640 (2009/08/15)
A simple method for determining the enantiomeric purity of profens (based on the carbon skeleton of 2-phenylpropionic acid) is discussed. The enantiomeric purity of a given profen can be determined by stereospecific DCC self-coupling to give a statistical diastereoisomeric mixture of racemic and meso- anhydrides. The relative ratio of diastereoisomers formed can be related to the enantiomeric excess of the original carboxylic acid.
Synthesis, characterisation and application of enantiomeric isotopomers of Evans' oxazolidinones
Boyd, Ewan,Chavda, Sameer,Coulbeck, Elliot,Coumbarides, Gregory S.,Dingjan, Marco,Eames, Jason,Flinn, Anthony,Krishnamurthy, Aarti K.,Namutebi, Mariam,Northen, Julian,Yohannes, Yonas
, p. 3406 - 3422 (2007/10/03)
The synthesis of a series of enantiomerically pure deuterium-labelled isotopomeric Evans' oxazolidinones is discussed.
Efficient parallel resolution of an active ester of 2-phenylpropionic acid using quasi-enantiomeric Evans' oxazolidinones
Coumbarides, Gregory S.,Dingjan, Marco,Eames, Jason,Flinn, Anthony,Northen, Julian,Yohannes, Yonas
, p. 2897 - 2902 (2007/10/03)
The parallel kinetic resolution of pentafluorophenyl 2-phenylpropionate using an equimolar combination of quasi-enantiomeric oxazolidinones is discussed. The levels of diastereocontrol were excellent leading to separable quasi-enantiomeric syn-oxazolidino
