1984-38-9

Basic information

• Product Name: 4-acetylaminohippuric acid
• Synonyms: 4-acetylaminohippuric acid;N-[4-(Acetylamino)benzoyl]glycine
• CAS NO: 1984-38-9
• Molecular Formula: C₁₁H₁₂N₂O₄
• Molecular Weight: 236.22
• Mol File: 1984-38-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 597.4°Cat760mmHg
• Flash Point: 315.1°C
• Appearance: /
• Density: 1.357g/cm³
• Vapor Pressure: 4.06E-15mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: 4-acetylaminohippuric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetylaminohippuric acid(1984-38-9)
• EPA Substance Registry System: 4-acetylaminohippuric acid(1984-38-9)

Safety Data

• Hazardous Substances Data: 1984-38-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H12N2O4/c1-7(14)13-9-4-2-8(3-5-9)11(17)12-6-10(15)16/h2-5H,6H2,1H3,(H,12,17)(H,13,14)(H,15,16)

Upstream product

• 556-08-1 p-(acetylamino)benzoic acid 
• 61-78-9 p-Aminohippuric acid 
• 75-36-5 acetyl chloride 
• 64480-74-6 p-acetaminohippuric acid methyl ester 

Downstream Products

• 14511-12-7 2-(4-acetylamino-phenyl)-4-(2,6-dimethyl-pyran-4-ylidene)-4H-oxazol-5-one 
• 64480-74-6 p-acetaminohippuric acid methyl ester 
• 904665-06-1 N-[1-hydrazinocarbonyl-2-(2-nitrophenyl)vinyl]-4-acetylaminobenzamide 
• 904665-28-7 3-(4-acetylaminophenyl)-5-(2-aminobenzyl)-1H-[1,2,4]triazin-6-one 
• 904665-20-9 3-(4-acetylaminophenyl)-5-(2-nitrobenzyl)-1H-[1,2,4]triazine-6-one 
• 904664-91-1 2-(4-acetylaminophenyl)-4-(2-nitrobezylidene)-4,5-dihydrooxazol-5-one 

Relevant articles and documents

Identification of urinary metabolites of orally administered N,N-dimethyl-p-toluidine in male F344 rats

The metabolism of orally administered N,N-dimethyl-p-toluidine (DMPT) in male F344 rats was investigated. The rat urinary metabolite profile was determined by analytical reverse-phase high performance liquid chromatography (HPLC). Four radiolabeled peaks were observed, isolated, and purified by solid-phase extraction (SPE) and preparative HPLC methods. The 4 peaks were identified as p-(N-acetylhydroxyamino)hippuric acid (M1), DMPT N-oxide (M2), N-methyl-p-toluidine (M3), and parent DMPT. Metabolites M1 and M2 were identified by spectrometric and spectroscopic methods, including mass fragmentation pattern identification from both liquid chromatography/mass spectrometry and gas chromatography/mass spectrometry, and from chemical analysis of nuclear magnetic resonance spectra. Structural confirmation of metabolite M2 was accomplished by comparison with a synthetic standard. Peaks M3 and the peak suspected to be DMPT were identified by comparison of their HPLC retention times and mass fragmentation patterns with authentic standards of N-methyl-p-toluidine and DMPT, respectively. DMPT metabolism is similar to that reported for N,N-dimethylaniline. Copyright Taylor & Francis Group, LLC.