19842-08-1Relevant articles and documents
OSMIUM-CONTAINING REDOX MEDIATOR
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, (2008/06/13)
A new group of Os(II) and Os(III) compounds useful as redox mediators in electrochemical biosensors is presented. These compounds have 1) low oxidation potential, 2) fast reaction kinetics between the electroactive center of an enzyme and the compound, 3) slow oxidation of osmium by oxygen, and 4) excellent solubility in aqueous medium. The figure shows is a cyclic voltammagram of the compound [Os(III)(bpy)2imCl]Cl2, wherein im is imidazolyl. These mediator compounds are particularly useful as a component of a reagent for measuring analytes from a biological fluid, such as blood.