19848-92-1

Upstream product

• 32601-86-8 2-chloro-3-methylquinoxaline 
• 14003-34-0 3-methyl-2-oxo-1,2-dihydroquinoxaline 
• 95-54-5 1,2-diamino-benzene 
• 51144-19-5 (3-methyl-quinoxalin-2-yl)-hydrazine 
• 98-88-4 benzoyl chloride 
• 326-06-7 1-Phenyl-4,4,4-trifluorobutane-1,3-dione 
• 100-52-7 benzaldehyde 

Relevant academic research and scientific papers

Hypervalent iodine-mediated synthesis of 1-aryl-4-methyl-1,2,4-triazolo[4, 3-a]quinoxalines by oxidative cyclization of arene carbaldehyde-3- methylquinoxalin-2-yl hydrazones

Arene carbaldehyde-3-methylquinoxalin-2-yl hydrazones (2) obtained by the condensation of 2-hydrazino-3-methylquinoxaline (1) with various aromatic aldehydes, on treatment with iodobenzene diacetate (IBD) in dichloromethane, undergo oxidative cyclization

TRIAZOLOPYRAZINE DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS

The present invention is directed to triazolopyrazine compounds of Formula (I). Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds as therapeutic agents treating neurological and psychiatric disorders.

Some novel observations on the reaction of 2-hydrazino-3-methylquinoxaline with trifluoromethyl-β-diketones

The reaction of 2-hydrazino-3-methylquinoxaline 1 with trifluoromethyl-β-diketones 2 not only yields the expected 5-trifluoromethyl-5-hydroxy-Δ2-pyrazolines 3a-3f and/or 3-trifluoromethylpyrazoles 4c-4f but also the unexpected products 1,2,4-tr