19853-95-3

Basic information

• Product Name: 1,4-bis[(2-aminoethyl)amino]anthracene-9,10-dione
• CAS NO: 19853-95-3
• Molecular Formula: C₁₈H₂₀N₄O₂
• Molecular Weight: 324.377
• Mol File: 19853-95-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 623.1°C at 760 mmHg
• Flash Point: 330.6°C
• Density: 1.36g/cm³
• Vapor Pressure: 1.91E-15mmHg at 25°C
• Refractive Index: 1.72
• CAS DataBase Reference: 1,4-bis[(2-aminoethyl)amino]anthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis[(2-aminoethyl)amino]anthracene-9,10-dione(19853-95-3)
• EPA Substance Registry System: 1,4-bis[(2-aminoethyl)amino]anthracene-9,10-dione(19853-95-3)

Safety Data

• Hazardous Substances Data: 19853-95-3(Hazardous Substances Data)

Usage

Family

Anthracenedione

Type

Synthetic molecule

Usage

Fluorescent dye and staining reagent

DNA Interaction

Intercalates with DNA

Applications

DNA-binding studies, visualization of DNA within cells

Potential Use

Cancer therapy (cytotoxic effects on cancer cells)

Additional Studies

Development of new materials and sensors

Molecular Structure

Unique molecular structure and properties

Upstream product

• 28736-42-7 1,4-difluoroanthracene-9,10-dione 
• 107-15-3 ethylenediamine 
• 19853-94-2 C₁₈H₂₂N₄O₂ 
• 182931-36-8 {2-[4-(2-tert-Butoxycarbonylamino-ethylamino)-9,10-dioxo-9,10-dihydro-anthracen-1-ylamino]-ethyl}-carbamic acid tert-butyl ester 
• 40498-13-3 2,3-dihydro-1,4-dihydroxyanthraquinone 
• 26786-15-2 1,4,9,9,10,10-hexachloroanthracene 
• 17648-03-2 9,10-Dihydroxy-2,3-dihydro-anthracene-1,4-dione 
• 602-25-5 1,4-dichloroanthraquinone 
• 70477-05-3 1,4-Bis-(2-aminoethyl-amino)-2,3-dihydro-anthrachinon 

Downstream Products

• 1327302-79-3 C₃₈H₃₈N₁₀O₈S₂ 

Relevant articles and documents

Development of colorimetric receptors for selective discrimination between isomeric dicarboxylate anions

Three new chromogenic receptors (1, 2, and 3) containing p-nitrophenyl or p-nitronaphthyl group appended to the thiourea units or containing p-nitrophenyl group appended to the urea moiety were synthesized and characterized. Upon addition of a series of i

Near-IR region absorbing 1,4-diaminoanthracene-9,10-dione motif?based?ratiometric chemosensors for Cu2+

1,4-Bis[2-aminoethylamino]anthracene-9,10-diones selectively bind with Cu2+ to form complexes with unusual selectivity under basic conditions. The deprotonation of the aryl amine NH in the case of these chemosensors causes a bathochromic shift in the absorption band from 585 nm and 635 nm to 725 nm and enables ratiometric estimation of Cu2+ between pH 8 and 12.

Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates

Two series of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates (BACs), ametantrone (AT)-amino acid conjugates (AACs) and mitoxantrone (MX)-amino acid conjugates (MACs), were designed and synthesized. The DNA binding of BACs was evaluated by