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198560-38-2

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198560-38-2 Usage

General Description

FMOC-L-INDOLINE-2-CARBOXYLIC ACID is a chemical compound with a molecular formula of C25H17NO4. It is commonly used in organic synthesis and as a building block in the production of pharmaceuticals and agrochemicals. FMOC-L-INDOLINE-2-CARBOXYLIC ACID is a derivative of indole and contains a carboxylic acid group, making it useful in the formation of peptide bonds and in the creation of peptide-based drugs. FMOC-L-INDOLINE-2-CARBOXYLIC ACID is also employed in the preparation of fluorescent dyes and as a reagent in the development of new compounds for research and drug discovery.

Check Digit Verification of cas no

The CAS Registry Mumber 198560-38-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,9,8,5,6 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 198560-38:
(8*1)+(7*9)+(6*8)+(5*5)+(4*6)+(3*0)+(2*3)+(1*8)=182
182 % 10 = 2
So 198560-38-2 is a valid CAS Registry Number.

198560-38-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(9H-fluoren-9-ylmethoxycarbonyl)-2,3-dihydroindole-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:198560-38-2 SDS

198560-38-2Downstream Products

198560-38-2Relevant articles and documents

6,5-Fused Ring, C2-Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects**

Akins, Nicholas S.,Ashpole, Nicole M.,Dudhipala, Narendar,Harris, Hannah M.,Keasling, Adam W.,Kim, Seong Jong,Le, Hoang V.,Majumdar, Soumyajit,Mishra, Nisha,Paris, Jason J.,Zjawiony, Jordan K.

, (2022/02/17)

Current common analgesics are mediated through the mu or kappa opioid receptor agonism. Unfortunately, selective mu or kappa receptor agonists often cause harmful side effects. However, ligands exhibiting dual agonism to the opioid receptors, such as to mu and kappa, or to mu and delta, have been suggested to temper undesirable adverse effects while retaining analgesic activity. Herein we report an introduction of various 6,5-fused rings to C2 of the salvinorin scaffold via an ester linker. In vitro studies showed that many of these compounds have dual agonism on kappa and mu opioid receptors. In vivo studies on the lead dual kappa and mu opioid receptor agonist demonstrated supraspinal thermal analgesic activity while avoiding anxiogenic effects in male mice, thus providing further strong evidence in support of the therapeutic advantages of dual opioid receptor agonists over selective opioid receptor agonists.

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